CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa constant

Enzyme Information

UniProtKB Entries (1)

P05106
ITB3_HUMAN
Homo sapiens
Integrin beta-3

PDB Structure

PDB 4O02
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Atomic basis for the species-specific inhibition of alpha V integrins by monoclonal antibody 17E6 is revealed by the crystal structure of alpha V beta 3 ectodomain-17E6 Fab complex.
Mahalingam, B., Van Agthoven, J.F., Xiong, J.P., Alonso, J.L., Adair, B.D., Rui, X., Anand, S., Mehrbod, M., Mofrad, M.R., Burger, C., Goodman, S.L., Arnaout, M.A.
J.Biol.Chem.