PDB 4kwf

PDB Links
Overview

PDB Information

PDB	4KWF
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones. Kimble-Hill, A.C., Parajuli, B., Chen, C.H., Mochly-Rosen, D., Hurley, T.D. J.Med.Chem.
Header	Oxidoreductase/Inhibitor
Released	2013-05-24
Resolution	2.310
CATH Insert Date	13 Apr, 2014

PDB Images (25)

4kwf

PDB 4kwf

4kwfA

PDB Chain 4kwfA

4kwfB

PDB Chain 4kwfB

4kwfC

PDB Chain 4kwfC

4kwfD

PDB Chain 4kwfD

4kwfE

PDB Chain 4kwfE

4kwfF

PDB Chain 4kwfF

4kwfG

PDB Chain 4kwfG

4kwfH

PDB Chain 4kwfH

4kwfA01

CATH Domain 4kwfA01

4kwfA02

CATH Domain 4kwfA02

4kwfB01

CATH Domain 4kwfB01

4kwfB02

CATH Domain 4kwfB02

4kwfC01

CATH Domain 4kwfC01

4kwfC02

CATH Domain 4kwfC02

4kwfD01

CATH Domain 4kwfD01

4kwfD02

CATH Domain 4kwfD02

4kwfE01

CATH Domain 4kwfE01

4kwfE02

CATH Domain 4kwfE02

4kwfF01

CATH Domain 4kwfF01

4kwfF02

CATH Domain 4kwfF02

4kwfG01

CATH Domain 4kwfG01

4kwfG02

CATH Domain 4kwfG02

4kwfH01

CATH Domain 4kwfH01

4kwfH02

CATH Domain 4kwfH02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	14 Apr, 2014	Chopped
B	14 Apr, 2014	Chopped
C	14 Apr, 2014	Chopped
D	14 Apr, 2014	Chopped
E	14 Apr, 2014	Chopped
F	14 Apr, 2014	Chopped
G	14 Apr, 2014	Chopped
H	14 Apr, 2014	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kwfA01	25 Apr, 2014	3.40.605.10	Assigned
4kwfA02	25 Apr, 2014	3.40.309.10	Assigned
4kwfB01	25 Apr, 2014	3.40.605.10	Assigned
4kwfB02	25 Apr, 2014	3.40.309.10	Assigned
4kwfC01	25 Apr, 2014	3.40.605.10	Assigned
4kwfC02	25 Apr, 2014	3.40.309.10	Assigned
4kwfD01	25 Apr, 2014	3.40.605.10	Assigned
4kwfD02	25 Apr, 2014	3.40.309.10	Assigned
4kwfE01	25 Apr, 2014	3.40.605.10	Assigned
4kwfE02	25 Apr, 2014	3.40.309.10	Assigned
4kwfF01	25 Apr, 2014	3.40.605.10	Assigned
4kwfF02	25 Apr, 2014	3.40.309.10	Assigned
4kwfG01	25 Apr, 2014	3.40.605.10	Assigned
4kwfG02	25 Apr, 2014	3.40.309.10	Assigned
4kwfH01	25 Apr, 2014	3.40.605.10	Assigned
4kwfH02	25 Apr, 2014	3.40.309.10	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial