PDB 4kv5

PDB Information

PDB4KV5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structures of a pan-specific antagonist antibody complexed to different isoforms of TGF beta reveal structural plasticity of antibody-antigen interactions.
Moulin, A., Mathieu, M., Lawrence, C., Bigelow, R., Levine, M., Hamel, C., Marquette, J.P., Le Parc, J., Loux, C., Ferrari, P., Capdevila, C., Dumas, J., Dumas, B., Rak, A., Bird, J., Qiu, H., Pan, C.Q., Edmunds, T., Wei, R.R.
Protein Sci.
HeaderImmune System
Released2013-05-22
Resolution3.000
CATH Insert Date05 Oct, 2014

PDB Images (25)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 06 Oct, 2014 Chopped
B 06 Oct, 2014 Chopped
C 06 Oct, 2014 Chopped
D 06 Oct, 2014 Chopped
E 06 Oct, 2014 Chopped
F 06 Oct, 2014 Chopped
G 06 Oct, 2014 Chopped
H 06 Oct, 2014 Chopped
I 06 Oct, 2014 Chopped
J 06 Oct, 2014 Chopped
K 06 Oct, 2014 Chopped
L 06 Oct, 2014 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4kv5A00 08 Oct, 2014 2.10.90.10 Assigned
4kv5B00 07 Oct, 2014 2.10.90.10 Assigned
4kv5C00 08 Oct, 2014 2.10.90.10 Assigned
4kv5D00 08 Oct, 2014 2.10.90.10 Assigned
4kv5E00 07 Oct, 2014 2.60.40.10 Assigned
4kv5F00 08 Oct, 2014 2.60.40.10 Assigned
4kv5G00 08 Oct, 2014 2.60.40.10 Assigned
4kv5H00 08 Oct, 2014 2.60.40.10 Assigned
4kv5I00 07 Oct, 2014 2.60.40.10 Assigned
4kv5J00 08 Oct, 2014 2.60.40.10 Assigned
4kv5K00 08 Oct, 2014 2.60.40.10 Assigned
4kv5L00 08 Oct, 2014 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P01137 TGFB1_HUMAN Homo sapiens Transforming growth factor beta-1 proprotein
P01137 TGFB1_HUMAN Homo sapiens Transforming growth factor beta-1 proprotein
P01137 TGFB1_HUMAN Homo sapiens Transforming growth factor beta-1 proprotein
P01137 TGFB1_HUMAN Homo sapiens Transforming growth factor beta-1 proprotein