PDB 4i9h

PDB Links
Overview

PDB Information

PDB	4I9H
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. Kohlmann, A., Zech, S.G., Li, F., Zhou, T., Squillace, R.M., Commodore, L., Greenfield, M.T., Lu, X., Miller, D.P., Huang, W.S., Qi, J., Thomas, R.M., Wang, Y., Zhang, S., Dodd, R., Liu, S., Xu, R., Xu, Y., Miret, J.J., Rivera, V., Clackson, T., Shakespeare, W.C., Zhu, X., Dalgarno, D.C. J.Med.Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-12-05
Resolution	2.170
CATH Insert Date	27 Jan, 2013

PDB Images (25)

4i9h

PDB 4i9h

4i9hA

PDB Chain 4i9hA

4i9hB

PDB Chain 4i9hB

4i9hC

PDB Chain 4i9hC

4i9hD

PDB Chain 4i9hD

4i9hE

PDB Chain 4i9hE

4i9hF

PDB Chain 4i9hF

4i9hG

PDB Chain 4i9hG

4i9hH

PDB Chain 4i9hH

4i9hA01

CATH Domain 4i9hA01

4i9hA02

CATH Domain 4i9hA02

4i9hB01

CATH Domain 4i9hB01

4i9hB02

CATH Domain 4i9hB02

4i9hC01

CATH Domain 4i9hC01

4i9hC02

CATH Domain 4i9hC02

4i9hD01

CATH Domain 4i9hD01

4i9hD02

CATH Domain 4i9hD02

4i9hE01

CATH Domain 4i9hE01

4i9hE02

CATH Domain 4i9hE02

4i9hF01

CATH Domain 4i9hF01

4i9hF02

CATH Domain 4i9hF02

4i9hG01

CATH Domain 4i9hG01

4i9hG02

CATH Domain 4i9hG02

4i9hH01

CATH Domain 4i9hH01

4i9hH02

CATH Domain 4i9hH02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	28 Jan, 2013	Chopped
B	28 Jan, 2013	Chopped
C	28 Jan, 2013	Chopped
D	28 Jan, 2013	Chopped
E	28 Jan, 2013	Chopped
F	28 Jan, 2013	Chopped
G	28 Jan, 2013	Chopped
H	28 Jan, 2013	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4i9hA01	02 Feb, 2013	3.40.50.720	Assigned
4i9hA02	02 Feb, 2013	3.90.110.10	Assigned
4i9hB01	02 Feb, 2013	3.40.50.720	Assigned
4i9hB02	02 Feb, 2013	3.90.110.10	Assigned
4i9hC01	02 Feb, 2013	3.40.50.720	Assigned
4i9hC02	02 Feb, 2013	3.90.110.10	Assigned
4i9hD01	02 Feb, 2013	3.40.50.720	Assigned
4i9hD02	02 Feb, 2013	3.90.110.10	Assigned
4i9hE01	02 Feb, 2013	3.40.50.720	Assigned
4i9hE02	02 Feb, 2013	3.90.110.10	Assigned
4i9hF01	02 Feb, 2013	3.40.50.720	Assigned
4i9hF02	02 Feb, 2013	3.90.110.10	Assigned
4i9hG01	02 Feb, 2013	3.40.50.720	Assigned
4i9hG02	02 Feb, 2013	3.90.110.10	Assigned
4i9hH01	02 Feb, 2013	3.40.50.720	Assigned
4i9hH02	02 Feb, 2013	3.90.110.10	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain