PDB 4hyf

PDB Links
Overview

PDB Information

PDB	4HYF
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structural Basis and SAR for G007-LK, a Lead Stage 1,2,4-Triazole Based Specific Tankyrase 1/2 Inhibitor. Voronkov, A., Holsworth, D.D., Waaler, J., Wilson, S.R., Ekblad, B., Perdreau-Dahl, H., Dinh, H., Drewes, G., Hopf, C., Morth, J.P., Krauss, S. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-11-13
Resolution	2.800
CATH Insert Date	28 Mar, 2013

PDB Images (7)

Image of CATH 4hyf

4hyf

PDB 4hyf

Image of CATH 4hyfA

4hyfA

PDB Chain 4hyfA

Image of CATH 4hyfB

4hyfB

PDB Chain 4hyfB

Image of CATH 4hyfC

4hyfC

PDB Chain 4hyfC

Image of CATH 4hyfA00

4hyfA00

CATH Domain 4hyfA00

Image of CATH 4hyfB00

4hyfB00

CATH Domain 4hyfB00

Image of CATH 4hyfC00

4hyfC00

CATH Domain 4hyfC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped
B	28 Mar, 2013	Chopped
C	28 Mar, 2013	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4hyfA00	01 Jul, 2013	3.90.228.10	Assigned
4hyfB00	01 Jul, 2013	3.90.228.10	Assigned
4hyfC00	14 Jun, 2013	3.90.228.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2