PDB 4h6j

PDB Information

PDB4H6J
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Cardoso, R., Love, R., Nilsson, C.L., Bergqvist, S., Nowlin, D., Yan, J., Liu, K.K., Zhu, J., Chen, P., Deng, Y.L., Dyson, H.J., Greig, M.J., Brooun, A.
Protein Sci.
HeaderTranscription
Released2012-09-19
Resolution1.520
CATH Insert Date30 Dec, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2012 Chopped
B 31 Dec, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4h6jA00 02 Jan, 2013 3.30.450.20 Assigned
4h6jB01 02 Jan, 2013 3.30.450.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27540 ARNT_HUMAN Homo sapiens Aryl hydrocarbon receptor nuclear translocator
Q16665 HIF1A_HUMAN Homo sapiens Hypoxia-inducible factor 1-alpha