PDB 4gid

PDB Information

PDB4GID
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure.
Ghosh, A.K., Venkateswara Rao, K., Yadav, N.D., Anderson, D.D., Gavande, N., Huang, X., Terzyan, S., Tang, J.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-08-08
Resolution2.000
CATH Insert Date04 Nov, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4gidA01 11 Nov, 2012 2.40.70.10 Assigned
4gidA02 11 Nov, 2012 2.40.70.10 Assigned
4gidB01 11 Nov, 2012 2.40.70.10 Assigned
4gidB02 11 Nov, 2012 2.40.70.10 Assigned
4gidC01 11 Nov, 2012 2.40.70.10 Assigned
4gidC02 11 Nov, 2012 2.40.70.10 Assigned
4gidD01 11 Nov, 2012 2.40.70.10 Assigned
4gidD02 11 Nov, 2012 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1