PDB Information

PDB4FZ3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate
Wu, J., Zhang, D., Chen, L., Li, J., Wang, J., Ning, C., Yu, N., Zhao, F., Chen, D., Chen, X., Chen, K., Jiang, H., Liu, H., Liu, D.
J.Med.Chem.
HeaderHydrolase/Hydrolase Substrate
Released2012-07-06
Resolution2.100
CATH Insert Date28 Mar, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4fz3A01 10 Apr, 2013 3.40.50.1220 Assigned
4fz3A02 10 Apr, 2013 3.30.1600.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9NTG7 SIR3_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-3, mitochondrial
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53