CATH Classification

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q9NTG7

UniProtKB Entries (1)

Q9NTG7
SIR3_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

PDB Structure

PDB 4FZ3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate
Wu, J., Zhang, D., Chen, L., Li, J., Wang, J., Ning, C., Yu, N., Zhao, F., Chen, D., Chen, X., Chen, K., Jiang, H., Liu, H., Liu, D.
J.Med.Chem.
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