PDB 3v8s

PDB Information

PDB3V8S
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Fragment-based and structure-guided discovery and optimization of rho kinase inhibitors.
Li, R., Martin, M.P., Liu, Y., Wang, B., Patel, R.A., Zhu, J.Y., Sun, N., Pireddu, R., Lawrence, N.J., Li, J., Haura, E.B., Sung, S.S., Guida, W.C., Schonbrunn, E., Sebti, S.M.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-12-23
Resolution2.290
CATH Insert Date12 Feb, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 13 Feb, 2012 Chopped
B 13 Feb, 2012 Chopped
C 13 Feb, 2012 Chopped
D 13 Feb, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3v8sA01 25 Apr, 2013 3.30.200.20 Assigned
3v8sA02 25 Apr, 2013 1.10.510.10 Assigned
3v8sB01 25 Apr, 2013 3.30.200.20 Assigned
3v8sB02 25 Apr, 2013 1.10.510.10 Assigned
3v8sC01 25 Apr, 2013 3.30.200.20 Assigned
3v8sC02 25 Apr, 2013 1.10.510.10 Assigned
3v8sD01 25 Apr, 2013 3.30.200.20 Assigned
3v8sD02 25 Apr, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
CATH-Gene3D is a Global Biodata Core Resource Learn more...