PDB 3twj

PDB Information

PDB3TWJ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer.
Patel, R.A., Forinash, K.D., Pireddu, R., Sun, Y., Sun, N., Martin, M.P., Schonbrunn, E., Lawrence, N.J., Sebti, S.M.
Cancer Res.
HeaderTransferase/Transferase Inhibitor
Released2011-09-21
Resolution2.900
CATH Insert Date04 Nov, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3twjA01 25 Apr, 2013 3.30.200.20 Assigned
3twjA02 25 Apr, 2013 1.10.510.10 Assigned
3twjB01 25 Apr, 2013 3.30.200.20 Assigned
3twjB02 25 Apr, 2013 1.10.510.10 Assigned
3twjC01 25 Apr, 2013 3.30.200.20 Assigned
3twjC02 25 Apr, 2013 1.10.510.10 Assigned
3twjD01 25 Apr, 2013 3.30.200.20 Assigned
3twjD02 25 Apr, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1