PDB 3twj
PDB Information
| PDB | 3TWJ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Homo sapiens |
| Primary Citation | RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer.
Cancer Res.
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2011-09-21 |
| Resolution | 2.900 |
| CATH Insert Date | 04 Nov, 2012 |
PDB Images (13)
3twj
PDB 3twj
3twjA
PDB Chain 3twjA
3twjB
PDB Chain 3twjB
3twjC
PDB Chain 3twjC
3twjD
PDB Chain 3twjD
3twjA01
CATH Domain 3twjA01
3twjA02
CATH Domain 3twjA02
3twjB01
CATH Domain 3twjB01
3twjB02
CATH Domain 3twjB02
3twjC01
CATH Domain 3twjC01
3twjC02
CATH Domain 3twjC02
3twjD01
CATH Domain 3twjD01
3twjD02
CATH Domain 3twjD02
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Nov, 2012 | Chopped |
| B | 05 Nov, 2012 | Chopped |
| C | 05 Nov, 2012 | Chopped |
| D | 05 Nov, 2012 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3twjA01 | 25 Apr, 2013 | 3.30.200.20 | Assigned |
| 3twjA02 | 25 Apr, 2013 | 1.10.510.10 | Assigned |
| 3twjB01 | 25 Apr, 2013 | 3.30.200.20 | Assigned |
| 3twjB02 | 25 Apr, 2013 | 1.10.510.10 | Assigned |
| 3twjC01 | 25 Apr, 2013 | 3.30.200.20 | Assigned |
| 3twjC02 | 25 Apr, 2013 | 1.10.510.10 | Assigned |
| 3twjD01 | 25 Apr, 2013 | 3.30.200.20 | Assigned |
| 3twjD02 | 25 Apr, 2013 | 1.10.510.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q13464 | ROCK1_HUMAN | Homo sapiens | Rho-associated protein kinase 1 |
| Q13464 | ROCK1_HUMAN | Homo sapiens | Rho-associated protein kinase 1 |
| Q13464 | ROCK1_HUMAN | Homo sapiens | Rho-associated protein kinase 1 |
| Q13464 | ROCK1_HUMAN | Homo sapiens | Rho-associated protein kinase 1 |
