PDB 3sad

PDB Information

PDB3SAD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
Structure-guided discovery of phenyl-diketo acids as potent inhibitors of M. tuberculosis malate synthase.
Krieger, I.V., Freundlich, J.S., Gawandi, V.B., Roberts, J.P., Gawandi, V.B., Sun, Q., Owen, J.L., Fraile, M.T., Huss, S.I., Lavandera, J.L., Ioerger, T.R., Sacchettini, J.C.
Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2011-06-02
Resolution1.820
CATH Insert Date11 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 12 Nov, 2012 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
3sadA01 07 Feb, 2017 3.20.20.360 Assigned
3sadA02 07 Feb, 2017 2.170.170.11 Assigned
3sadA03 07 Feb, 2017 1.20.1220.12 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P9WK17 MASZ_MYCTU Mycobacterium tuberculosis H37Rv Malate synthase G