PDB Information

PDB3ODI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin).
Kuglstatter, A., Mueller, F., Kusznir, E., Gsell, B., Stihle, M., Thoma, R., Benz, J., Aspeslet, L., Freitag, D., Hennig, M.
Acta Crystallogr.,Sect.D
HeaderIsomerase/Immunosuppressant
Released2010-08-11
Resolution2.2
CATH Insert Date20 Feb, 2011

PDB Images (31)

PDB Chains (20)

Chain ID Date inserted into CATH CATH Status
A 21 Feb, 2011 Chopped
B 21 Feb, 2011 Rejected
C 21 Feb, 2011 Chopped
D 21 Feb, 2011 Rejected
E 21 Feb, 2011 Chopped
F 21 Feb, 2011 Rejected
G 21 Feb, 2011 Chopped
H 21 Feb, 2011 Rejected
I 21 Feb, 2011 Chopped
J 21 Feb, 2011 Rejected
K 21 Feb, 2011 Chopped
L 21 Feb, 2011 Rejected
M 21 Feb, 2011 Chopped
N 21 Feb, 2011 Rejected
O 21 Feb, 2011 Chopped
P 21 Feb, 2011 Rejected
Q 21 Feb, 2011 Chopped
R 21 Feb, 2011 Rejected
S 21 Feb, 2011 Chopped
T 21 Feb, 2011 Rejected

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
3odiA00 05 Feb, 2013 Holding pen
3odiC00 04 Feb, 2013 Holding pen
3odiE00 04 Feb, 2013 Holding pen
3odiG00 04 Feb, 2013 Holding pen
3odiI00 04 Feb, 2013 Holding pen
3odiK00 05 Feb, 2013 Holding pen
3odiM00 04 Feb, 2013 Holding pen
3odiO00 04 Feb, 2013 Holding pen
3odiQ00 05 Feb, 2013 Holding pen
3odiS00 05 Feb, 2013 Holding pen

Uniprot Entries (10)

Accession Gene ID Taxon Description
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A
P62937 PPIA_HUMAN Homo sapiens Cyclophilin A