PDB 3lz6

PDB Links
Overview

PDB Information

PDB	3LZ6
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Cavia porcellus
Primary Citation	The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors. Cheng, H., Hoffman, J., Le, P., Nair, S.K., Cripps, S., Matthews, J., Smith, C., Yang, M., Kupchinsky, S., Dress, K., Edwards, M., Cole, B., Walters, E., Loh, C., Ermolieff, J., Fanjul, A., Bhat, G.B., Herrera, J., Pauly, T., Hosea, N., Paderes, G., Rejto, P. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2010-03-01
Resolution	1.840
CATH Insert Date	08 May, 2011

PDB Images (9)

Image of CATH 3lz6

3lz6

PDB 3lz6

Image of CATH 3lz6A

3lz6A

PDB Chain 3lz6A

Image of CATH 3lz6B

3lz6B

PDB Chain 3lz6B

Image of CATH 3lz6C

3lz6C

PDB Chain 3lz6C

Image of CATH 3lz6D

3lz6D

PDB Chain 3lz6D

Image of CATH 3lz6A00

3lz6A00

CATH Domain 3lz6A00

Image of CATH 3lz6B00

3lz6B00

CATH Domain 3lz6B00

Image of CATH 3lz6C00

3lz6C00

CATH Domain 3lz6C00

Image of CATH 3lz6D00

3lz6D00

CATH Domain 3lz6D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	09 May, 2011	Chopped
B	09 May, 2011	Chopped
C	09 May, 2011	Chopped
D	09 May, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3lz6A00	15 May, 2011	3.40.50.720	Assigned
3lz6B00	15 May, 2011	3.40.50.720	Assigned
3lz6C00	15 May, 2011	3.40.50.720	Assigned
3lz6D00	14 May, 2011	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q6QLL4	DHI1_CAVPO	Cavia porcellus	Corticosteroid 11-beta-dehydrogenase isozyme 1
Q6QLL4	DHI1_CAVPO	Cavia porcellus	Corticosteroid 11-beta-dehydrogenase isozyme 1
Q6QLL4	DHI1_CAVPO	Cavia porcellus	Corticosteroid 11-beta-dehydrogenase isozyme 1
Q6QLL4	DHI1_CAVPO	Cavia porcellus	Corticosteroid 11-beta-dehydrogenase isozyme 1