PDB 3lox

PDB Links
Overview

PDB Information

PDB	3LOX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus subtype 1a
Primary Citation	The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor. Bennett, F., Huang, Y., Hendrata, S., Lovey, R., Bogen, S.L., Pan, W., Guo, Z., Prongay, A., Chen, K.X., Arasappan, A., Venkatraman, S., Velazquez, F., Nair, L., Sannigrahi, M., Tong, X., Pichardo, J., Cheng, K.C., Girijavallabhan, V.M., Saksena, A.K., Njoroge, F.G. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2010-02-04
Resolution	2.650
CATH Insert Date	27 Feb, 2011

PDB Images (9)

Image of CATH 3lox

3lox

PDB 3lox

Image of CATH 3loxA

3loxA

PDB Chain 3loxA

Image of CATH 3loxB

3loxB

PDB Chain 3loxB

Image of CATH 3loxC

3loxC

PDB Chain 3loxC

Image of CATH 3loxD

3loxD

PDB Chain 3loxD

Image of CATH 3loxA01

3loxA01

CATH Domain 3loxA01

Image of CATH 3loxA02

3loxA02

CATH Domain 3loxA02

Image of CATH 3loxC01

3loxC01

CATH Domain 3loxC01

Image of CATH 3loxC02

3loxC02

CATH Domain 3loxC02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	28 Feb, 2011	Chopped
B	28 Feb, 2011	Rejected
C	28 Feb, 2011	Chopped
D	28 Feb, 2011	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3loxA01	08 Feb, 2013	2.40.10.120	Assigned
3loxA02	08 Feb, 2013	2.40.10.10	Assigned
3loxC01	07 Feb, 2013	2.40.10.120	Assigned
3loxC02	07 Feb, 2013	2.40.10.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9ELS8	Q9ELS8_9HEPC	Hepatitis C virus subtype 1a	Genome polyprotein
Q9ELS8	Q9ELS8_9HEPC	Hepatitis C virus subtype 1a	Genome polyprotein