PDB 3jsu

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Overview

PDB Information

PDB	3JSU
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Plasmodium falciparum
Primary Citation	Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate Nzila, A., Rottmann, M., Chitnumsub, P., Kiara, S.M., Kamchonwongpaisan, S., Maneeruttanarungroj, C., Taweechai, S., Yeung, B.K., Goh, A., Lakshminarayana, S.B., Zou, B., Wong, J., Ma, N.L., Weaver, M., Keller, T.H., Dartois, V., Wittlin, S., Brun, R., Yuthavong, Y., Diagana, T.T. Antimicrob.Agents Chemother.
Header	Oxidoreductase, Transferase
Released	2009-09-11
Resolution	2.700
CATH Insert Date	15 Aug, 2010

PDB Images (9)

Image of CATH 3jsu

3jsu

PDB 3jsu

Image of CATH 3jsuA

3jsuA

PDB Chain 3jsuA

Image of CATH 3jsuB

3jsuB

PDB Chain 3jsuB

Image of CATH 3jsuA01

3jsuA01

CATH Domain 3jsuA01

Image of CATH 3jsuA02

3jsuA02

CATH Domain 3jsuA02

Image of CATH 3jsuA03

3jsuA03

CATH Domain 3jsuA03

Image of CATH 3jsuB01

3jsuB01

CATH Domain 3jsuB01

Image of CATH 3jsuB02

3jsuB02

CATH Domain 3jsuB02

Image of CATH 3jsuB03

3jsuB03

CATH Domain 3jsuB03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2010	Chopped
B	16 Aug, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3jsuA01	29 Aug, 2013	3.40.430.10	Assigned
3jsuA02	29 Aug, 2013	6.10.250.2210	Assigned
3jsuA03	29 Aug, 2013	3.30.572.10	Assigned
3jsuB01	29 Aug, 2013	3.40.430.10	Assigned
3jsuB02	29 Aug, 2013	6.10.250.2210	Assigned
3jsuB03	29 Aug, 2013	3.30.572.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
D9N170	D9N170_PLAFA	Plasmodium falciparum	Bifunctional dihydrofolate reductase-thymidylate synthase
D9N170	D9N170_PLAFA	Plasmodium falciparum	Bifunctional dihydrofolate reductase-thymidylate synthase