PDB 3h42

PDB Information

PDB3H42
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Chan, J.C., Piper, D.E., Cao, Q., Liu, D., King, C., Wang, W., Tang, J., Liu, Q., Higbee, J., Xia, Z., Di, Y., Shetterly, S., Arimura, Z., Salomonis, H., Romanow, W.G., Thibault, S.T., Zhang, R., Cao, P., Yang, X.P., Yu, T., Lu, M., Retter, M.W., Kwon, G., Henne, K., Pan, O., Tsai, M.M., Fuchslocher, B., Yang, E., Zhou, L., Lee, K.J., Daris, M., Sheng, J., Wang, Y., Shen, W.D., Yeh, W.C., Emery, M., Walker, N.P., Shan, B., Schwarz, M., Jackson, S.M.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase/Immune System
Released2009-04-17
Resolution2.300
CATH Insert Date16 Aug, 2009

PDB Images (12)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
H 16 Aug, 2009 Chopped
L 16 Aug, 2009 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
3h42A01 04 Feb, 2013 3.30.70.80 Assigned
3h42B01 09 Oct, 2013 3.40.50.200 Assigned
3h42B02 09 Oct, 2013 2.60.120.690 Assigned
3h42H01 18 May, 2010 2.60.40.10 Assigned
3h42H02 18 May, 2010 2.60.40.10 Assigned
3h42L01 18 May, 2010 2.60.40.10 Assigned
3h42L02 18 May, 2010 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9