PDB 3ey4

PDB Links
Overview

PDB Information

PDB	3EY4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model Christopher, F., Bartberger, M.D., Bercot, E.A., Chen, M., Cupples, R., Emery, M., Fretland, J., Guram, A., Hale, C., Han, N.H., Hickman, D., Hungate, R.W., Hayashi, M., Komorowski, R., Liu, Q.Y., Matsumoto, G., Jean, D.J.St., Ursu, S., Voniant, M., Xu, G.F., Ye, Q.P., Yuan, C., Zhang, J.D., Zhang, X.P., Tu, H., Wang, M.H. To be Published
Header	Oxidoreductase
Released	2008-10-17
Resolution	3.000
CATH Insert Date	13 Nov, 2008

PDB Images (9)

Image of CATH 3ey4

3ey4

PDB 3ey4

Image of CATH 3ey4A

3ey4A

PDB Chain 3ey4A

Image of CATH 3ey4B

3ey4B

PDB Chain 3ey4B

Image of CATH 3ey4C

3ey4C

PDB Chain 3ey4C

Image of CATH 3ey4D

3ey4D

PDB Chain 3ey4D

Image of CATH 3ey4A00

3ey4A00

CATH Domain 3ey4A00

Image of CATH 3ey4B00

3ey4B00

CATH Domain 3ey4B00

Image of CATH 3ey4C00

3ey4C00

CATH Domain 3ey4C00

Image of CATH 3ey4D00

3ey4D00

CATH Domain 3ey4D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	13 Nov, 2008	Chopped
B	13 Nov, 2008	Chopped
C	13 Nov, 2008	Chopped
D	13 Nov, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ey4A00	05 Dec, 2008	3.40.50.720	Assigned
3ey4B00	05 Dec, 2008	3.40.50.720	Assigned
3ey4C00	05 Dec, 2008	3.40.50.720	Assigned
3ey4D00	05 Dec, 2008	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1