PDB 3eoa
PDB Information
| PDB | 3EOA |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA
|
| Header | Immune System/Cell Adhesion |
| Released | 2008-09-26 |
| Resolution | 2.800 |
| CATH Insert Date | 16 Aug, 2009 |
PDB Images (17)
3eoa
PDB 3eoa
3eoaA
PDB Chain 3eoaA
3eoaB
PDB Chain 3eoaB
3eoaH
PDB Chain 3eoaH
3eoaI
PDB Chain 3eoaI
3eoaJ
PDB Chain 3eoaJ
3eoaL
PDB Chain 3eoaL
3eoaA01
CATH Domain 3eoaA01
3eoaA02
CATH Domain 3eoaA02
3eoaB01
CATH Domain 3eoaB01
3eoaB02
CATH Domain 3eoaB02
3eoaH01
CATH Domain 3eoaH01
3eoaH02
CATH Domain 3eoaH02
3eoaI00
CATH Domain 3eoaI00
3eoaJ00
CATH Domain 3eoaJ00
3eoaL01
CATH Domain 3eoaL01
3eoaL02
CATH Domain 3eoaL02
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2009 | Chopped |
| B | 16 Aug, 2009 | Chopped |
| H | 16 Aug, 2009 | Chopped |
| I | 16 Aug, 2009 | Chopped |
| J | 16 Aug, 2009 | Chopped |
| L | 16 Aug, 2009 | Chopped |
CATH Domains (10)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3eoaA01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaA02 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaB01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaB02 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaH01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaH02 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaI00 | 29 Sep, 2009 | 3.40.50.410 | Assigned |
| 3eoaJ00 | 29 Sep, 2009 | 3.40.50.410 | Assigned |
| 3eoaL01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eoaL02 | 18 May, 2010 | 2.60.40.10 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P20701 | ITAL_HUMAN | Homo sapiens | Integrin alpha-L |
| P20701 | ITAL_HUMAN | Homo sapiens | Integrin alpha-L |
