PDB 3eoa

PDB Information

PDB3EOA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Li, S., Wang, H., Peng, B., Zhang, M., Zhang, D., Hou, S., Guo, Y., Ding, J.
Proc.Natl.Acad.Sci.USA
HeaderImmune System/Cell Adhesion
Released2008-09-26
Resolution2.800
CATH Insert Date16 Aug, 2009

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
H 16 Aug, 2009 Chopped
I 16 Aug, 2009 Chopped
J 16 Aug, 2009 Chopped
L 16 Aug, 2009 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
3eoaA01 18 May, 2010 2.60.40.10 Assigned
3eoaA02 18 May, 2010 2.60.40.10 Assigned
3eoaB01 18 May, 2010 2.60.40.10 Assigned
3eoaB02 18 May, 2010 2.60.40.10 Assigned
3eoaH01 18 May, 2010 2.60.40.10 Assigned
3eoaH02 18 May, 2010 2.60.40.10 Assigned
3eoaI00 29 Sep, 2009 3.40.50.410 Assigned
3eoaJ00 29 Sep, 2009 3.40.50.410 Assigned
3eoaL01 18 May, 2010 2.60.40.10 Assigned
3eoaL02 18 May, 2010 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P20701 ITAL_HUMAN Homo sapiens Integrin alpha-L
P20701 ITAL_HUMAN Homo sapiens Integrin alpha-L