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1 keywords

CATH Domain 3eoaA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

P20701
ITAL_HUMAN
Homo sapiens
Integrin alpha-L

PDB Structure

PDB 3EOA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Li, S., Wang, H., Peng, B., Zhang, M., Zhang, D., Hou, S., Guo, Y., Ding, J.
Proc.Natl.Acad.Sci.USA
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