PDB 3cdb

PDB Information

PDB3CDB
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution2.300
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3cdbA01 26 Jul, 2008 1.10.3270.10 Assigned
3cdbA02 26 Jul, 2008 3.90.770.10 Assigned
3cdbA03 26 Jul, 2008 3.30.70.420 Assigned
3cdbB01 26 Jul, 2008 1.10.3270.10 Assigned
3cdbB02 26 Jul, 2008 3.90.770.10 Assigned
3cdbB03 26 Jul, 2008 3.30.70.420 Assigned
3cdbC01 26 Jul, 2008 1.10.3270.10 Assigned
3cdbC02 26 Jul, 2008 3.90.770.10 Assigned
3cdbC03 26 Jul, 2008 3.30.70.420 Assigned
3cdbD01 26 Jul, 2008 1.10.3270.10 Assigned
3cdbD02 26 Jul, 2008 3.90.770.10 Assigned
3cdbD03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase