PDB 3cct

PDB Information

PDB3CCT
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution2.120
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3cctA01 26 Jul, 2008 1.10.3270.10 Assigned
3cctA02 26 Jul, 2008 3.90.770.10 Assigned
3cctA03 26 Jul, 2008 3.30.70.420 Assigned
3cctB01 25 Jul, 2008 1.10.3270.10 Assigned
3cctB02 25 Jul, 2008 3.90.770.10 Assigned
3cctB03 25 Jul, 2008 3.30.70.420 Assigned
3cctC01 26 Jul, 2008 1.10.3270.10 Assigned
3cctC02 26 Jul, 2008 3.90.770.10 Assigned
3cctC03 26 Jul, 2008 3.30.70.420 Assigned
3cctD01 26 Jul, 2008 1.10.3270.10 Assigned
3cctD02 26 Jul, 2008 3.90.770.10 Assigned
3cctD03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase