PDB Information

PDB3AH8
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceRattus norvegicus
Primary Citation
Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
Nishimura, A., Kitano, K., Takasaki, J., Taniguchi, M., Mizuno, N., Tago, K., Hakoshima, T., Itoh, H.
Proc.Natl.Acad.Sci.USA
HeaderSignaling Protein/Inhibitor
Released2010-04-20
Resolution2.900
CATH Insert Date15 Aug, 2010

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped
B 16 Aug, 2010 Chopped
G 16 Aug, 2010 Chopped
Y 16 Aug, 2010 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3ah8A01 15 Sep, 2010 3.40.50.300 Assigned
3ah8A02 15 Sep, 2010 1.10.400.10 Assigned
3ah8B00 21 Mar, 2011 2.130.10.10 Assigned
3ah8G00 15 Sep, 2010 4.10.260.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P10824 GNAI1_RAT Rattus norvegicus Guanine nucleotide-binding protein G(i) subunit alpha-1
P63212 GBG2_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P21279 GNAQ_MOUSE Mus musculus Guanine nucleotide-binding protein G(q) subunit alpha
P62871 GBB1_BOVIN Bos taurus Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1