CATH Classification

Domain Context

CATH Clusters

Superfamily GI Alpha 1, domain 2-like
Functional Family Guanine nucleotide-binding protein subunit alpha-11

Enzyme Information

UniProtKB Entries (3)

P21279
GNAQ_MOUSE
Mus musculus
Guanine nucleotide-binding protein G(q) subunit alpha
P10824
GNAI1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(i) subunit alpha-1
P62871
GBB1_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

PDB Structure

PDB 3AH8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
Nishimura, A., Kitano, K., Takasaki, J., Taniguchi, M., Mizuno, N., Tago, K., Hakoshima, T., Itoh, H.
Proc.Natl.Acad.Sci.USA