PDB Information

PDB2V0T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceTRYPANOSOMA BRUCEI BRUCEI
Primary Citation
Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM.
Alahuhta, M., Casteleijn, M.G., Neubauer, P., Wierenga, R.K.
Acta Crystallogr. D Biol. Crystallogr.
HeaderIsomerase
Released2007-05-17
Resolution2.200
CATH Insert Date21 Feb, 2008

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 21 Feb, 2008 Chopped
B 21 Feb, 2008 Chopped
C 21 Feb, 2008 Chopped
D 21 Feb, 2008 Chopped
E 21 Feb, 2008 Chopped
F 21 Feb, 2008 Chopped
G 21 Feb, 2008 Chopped
H 21 Feb, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2v0tA00 22 Feb, 2008 3.20.20.70 Assigned
2v0tB00 23 Feb, 2008 3.20.20.70 Assigned
2v0tC00 23 Feb, 2008 3.20.20.70 Assigned
2v0tD00 23 Feb, 2008 3.20.20.70 Assigned
2v0tE00 23 Feb, 2008 3.20.20.70 Assigned
2v0tF00 23 Feb, 2008 3.20.20.70 Assigned
2v0tG00 23 Feb, 2008 3.20.20.70 Assigned
2v0tH00 23 Feb, 2008 3.20.20.70 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal
P04789 TPIS_TRYBB Trypanosoma brucei brucei Triosephosphate isomerase, glycosomal