PDB 2p59

PDB Information

PDB2P59
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHepatitis C virus
Primary Citation
Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.
Perni, R.B., Chandorkar, G., Cottrell, K.M., Gates, C.A., Lin, C., Lin, K., Luong, Y.P., Maxwell, J.P., Murcko, M.A., Pitlik, J., Rao, G., Schairer, W.C., Van Drie, J., Wei, Y.
Bioorg.Med.Chem.Lett.
HeaderViral Protein
Released2007-03-14
Resolution2.900
CATH Insert Date21 Feb, 2008

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Feb, 2008 Chopped
B 21 Feb, 2008 Chopped
C 21 Feb, 2008 Rejected
D 21 Feb, 2008 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2p59A01 22 Feb, 2008 2.40.10.120 Assigned
2p59A02 22 Feb, 2008 2.40.10.10 Assigned
2p59B01 23 Feb, 2008 2.40.10.120 Assigned
2p59B02 23 Feb, 2008 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q91RS4 Q91RS4_9HEPC Hepacivirus C NS3 protease
Q91RS4 Q91RS4_9HEPC Hepacivirus C NS3 protease
P27958 POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein
P27958 POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein