PDB 2p59

PDB Links
Overview

PDB Information

PDB	2P59
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Hepatitis C virus
Primary Citation	Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics. Perni, R.B., Chandorkar, G., Cottrell, K.M., Gates, C.A., Lin, C., Lin, K., Luong, Y.P., Maxwell, J.P., Murcko, M.A., Pitlik, J., Rao, G., Schairer, W.C., Van Drie, J., Wei, Y. Bioorg.Med.Chem.Lett.
Header	Viral Protein
Released	2007-03-14
Resolution	2.900
CATH Insert Date	21 Feb, 2008

PDB Images (9)

Image of CATH 2p59

2p59

PDB 2p59

Image of CATH 2p59A

2p59A

PDB Chain 2p59A

Image of CATH 2p59B

2p59B

PDB Chain 2p59B

Image of CATH 2p59C

2p59C

PDB Chain 2p59C

Image of CATH 2p59D

2p59D

PDB Chain 2p59D

Image of CATH 2p59A01

2p59A01

CATH Domain 2p59A01

Image of CATH 2p59A02

2p59A02

CATH Domain 2p59A02

Image of CATH 2p59B01

2p59B01

CATH Domain 2p59B01

Image of CATH 2p59B02

2p59B02

CATH Domain 2p59B02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	21 Feb, 2008	Chopped
B	21 Feb, 2008	Chopped
C	21 Feb, 2008	Rejected
D	21 Feb, 2008	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2p59A01	22 Feb, 2008	2.40.10.120	Assigned
2p59A02	22 Feb, 2008	2.40.10.10	Assigned
2p59B01	23 Feb, 2008	2.40.10.120	Assigned
2p59B02	23 Feb, 2008	2.40.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q91RS4	Q91RS4_9HEPC	Hepacivirus C	NS3 protease
Q91RS4	Q91RS4_9HEPC	Hepacivirus C	NS3 protease
P27958	POLG_HCVH	Hepatitis C virus (isolate H)	Genome polyprotein
P27958	POLG_HCVH	Hepatitis C virus (isolate H)	Genome polyprotein