PDB 2g1q

PDB Information

PDB2G1Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP.
Cox, C.D., Torrent, M., Breslin, M.J., Mariano, B.J., Whitman, D.B., Coleman, P.J., Buser, C.A., Walsh, E.S., Hamilton, K., Schaber, M.D., Lobell, R.B., Tao, W., South, V.J., Kohl, N.E., Yan, Y., Kuo, L.C., Prueksaritanont, T., Slaughter, D.E., Li, C., Mahan, E., Lu, B., Hartman, G.D.
Bioorg.Med.Chem.Lett.
HeaderCell Cycle
Released2006-02-14
Resolution2.510
CATH Insert Date05 Oct, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Oct, 2006 Chopped
B 05 Oct, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2g1qA00 15 Oct, 2006 3.40.850.10 Assigned
2g1qB00 02 Nov, 2006 3.40.850.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P52732 KIF11_HUMAN Homo sapiens Kinesin-like protein KIF11
P52732 KIF11_HUMAN Homo sapiens Kinesin-like protein KIF11
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