CATH Domain 2g1qA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.850	Kinesin
	3.40.850.10	Kinesin motor domain

Domain Context

CATH Clusters

Superfamily	Kinesin motor domain
Functional Family	Kinesin-like protein KIF11

Enzyme Information

UniProtKB Entries (1)

KIF11_HUMAN

Homo sapiens

Kinesin-like protein KIF11

PDB Structure

PDB	2G1Q
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP. Cox, C.D., Torrent, M., Breslin, M.J., Mariano, B.J., Whitman, D.B., Coleman, P.J., Buser, C.A., Walsh, E.S., Hamilton, K., Schaber, M.D., Lobell, R.B., Tao, W., South, V.J., Kohl, N.E., Yan, Y., Kuo, L.C., Prueksaritanont, T., Slaughter, D.E., Li, C., Mahan, E., Lu, B., Hartman, G.D. Bioorg.Med.Chem.Lett.