PDB 2fm2

PDB Links
Overview

PDB Information

PDB	2FM2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus
Primary Citation	Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations Yi, M., Tong, X., Skelton, A., Chase, R., Chen, T., Prongay, A., Bogen, S.L., Saksena, A.K., Njoroge, F.G., Veselenak, R.L., Pyles, R.B., Bourne, N., Malcolm, B.A., Lemon, S.M. J.Biol.Chem.
Header	Hydrolase
Released	2006-01-06
Resolution	2.700
CATH Insert Date	05 Mar, 2006

PDB Images (9)

Image of CATH 2fm2

2fm2

PDB 2fm2

Image of CATH 2fm2A

2fm2A

PDB Chain 2fm2A

Image of CATH 2fm2B

2fm2B

PDB Chain 2fm2B

Image of CATH 2fm2C

2fm2C

PDB Chain 2fm2C

Image of CATH 2fm2D

2fm2D

PDB Chain 2fm2D

Image of CATH 2fm2A01

2fm2A01

CATH Domain 2fm2A01

Image of CATH 2fm2A02

2fm2A02

CATH Domain 2fm2A02

Image of CATH 2fm2C01

2fm2C01

CATH Domain 2fm2C01

Image of CATH 2fm2C02

2fm2C02

CATH Domain 2fm2C02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	15 Mar, 2006	Chopped
B	15 Mar, 2006	Rejected
C	15 Mar, 2006	Chopped
D	15 Mar, 2006	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2fm2A01	17 Mar, 2006	2.40.10.120	Assigned
2fm2A02	17 Mar, 2006	2.40.10.10	Assigned
2fm2C01	17 Mar, 2006	2.40.10.120	Assigned
2fm2C02	17 Mar, 2006	2.40.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9ELS8	Q9ELS8_9HEPC	Hepatitis C virus subtype 1a	Genome polyprotein
Q9ELS8	Q9ELS8_9HEPC	Hepatitis C virus subtype 1a	Genome polyprotein
Q9ELS8	Q9ELS8_9HEPC	Hepatitis C virus subtype 1a	Genome polyprotein
Q9ELS8	Q9ELS8_9HEPC	Hepatitis C virus subtype 1a	Genome polyprotein