PDB 2acl

PDB Information

PDB2ACL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of substituted maleimides as liver x receptor agonists and determination of a ligand-bound crystal structure.
Jaye, M.C., Krawiec, J.A., Campobasso, N., Smallwood, A., Qiu, C., Lu, Q., Kerrigan, J.J., De Los Frailes Alvaro, M., Laffitte, B., Liu, W.S., Marino, J.P., Meyer, C.R., Nichols, J.A., Parks, D.J., Perez, P., Sarov-Blat, L., Seepersaud, S.D., Steplewski, K.M., Thompson, S.K., Wang, P., Watson, M.A., Webb, C.L., Haigh, D., Caravella, J.A., Macphee, C.H., Willson, T.M., Collins, J.L.
J.Med.Chem.
HeaderTranscription
Released2005-07-19
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Chopped
G 05 Mar, 2006 Chopped
H 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2aclA00 17 Nov, 2006 1.10.565.10 Assigned
2aclB00 28 Nov, 2006 1.10.565.10 Assigned
2aclC00 28 Nov, 2006 1.10.565.10 Assigned
2aclD00 28 Nov, 2006 1.10.565.10 Assigned
2aclE00 29 Nov, 2006 1.10.565.10 Assigned
2aclF00 29 Nov, 2006 1.10.565.10 Assigned
2aclG00 28 Nov, 2006 1.10.565.10 Assigned
2aclH00 17 Nov, 2006 1.10.565.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P19793 RXRA_HUMAN Homo sapiens Retinoic acid receptor RXR-alpha
P19793 RXRA_HUMAN Homo sapiens Retinoic acid receptor RXR-alpha
P19793 RXRA_HUMAN Homo sapiens Retinoic acid receptor RXR-alpha
Q9Z0Y9 NR1H3_MOUSE Mus musculus Oxysterols receptor LXR-alpha
P19793 RXRA_HUMAN Homo sapiens Retinoic acid receptor RXR-alpha
Q9Z0Y9 NR1H3_MOUSE Mus musculus Oxysterols receptor LXR-alpha
Q9Z0Y9 NR1H3_MOUSE Mus musculus Oxysterols receptor LXR-alpha
Q9Z0Y9 NR1H3_MOUSE Mus musculus Oxysterols receptor LXR-alpha