CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (2)

P19793
RXRA_HUMAN
Homo sapiens
Retinoic acid receptor RXR-alpha
Q9Z0Y9
NR1H3_MOUSE
Mus musculus
Oxysterols receptor LXR-alpha

PDB Structure

PDB 2ACL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Discovery of substituted maleimides as liver x receptor agonists and determination of a ligand-bound crystal structure.
Jaye, M.C., Krawiec, J.A., Campobasso, N., Smallwood, A., Qiu, C., Lu, Q., Kerrigan, J.J., De Los Frailes Alvaro, M., Laffitte, B., Liu, W.S., Marino, J.P., Meyer, C.R., Nichols, J.A., Parks, D.J., Perez, P., Sarov-Blat, L., Seepersaud, S.D., Steplewski, K.M., Thompson, S.K., Wang, P., Watson, M.A., Webb, C.L., Haigh, D., Caravella, J.A., Macphee, C.H., Willson, T.M., Collins, J.L.
J.Med.Chem.
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