PDB Information

PDB1WOK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors.
Iwashita, A., Hattori, K., Yamamoto, H., Ishida, J., Kido, Y., Kamijo, K., Murano, K., Miyake, H., Kinoshita, T., Warizaya, M., Ohkubo, M., Matsuoka, N., Mutoh, S.
Febs Lett.
HeaderTransferase
Released2004-08-20
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
1wokA01 09 Mar, 2006 1.20.142.10 Assigned
1wokA02 09 Mar, 2006 3.90.228.10 Assigned
1wokB01 09 Mar, 2006 1.20.142.10 Assigned
1wokB02 09 Mar, 2006 3.90.228.10 Assigned
1wokC01 09 Mar, 2006 1.20.142.10 Assigned
1wokC02 09 Mar, 2006 3.90.228.10 Assigned
1wokD01 09 Mar, 2006 1.20.142.10 Assigned
1wokD02 09 Mar, 2006 3.90.228.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1