PDB 1h7w

PDB Information

PDB1H7W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli DH5[alpha]
Gene SourceSUS SCROFA
Primary Citation
Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil.
Dobritzsch, D., Schneider, G., Schnackerz, K.D., Lindqvist, Y.
EMBO J.
HeaderElectron Transfer
Released2001-01-18
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (25)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (20)

Domain ID Date inserted into CATH Superfamily CATH Status
1h7wA01 19 Dec, 2006 3.30.70.20 Assigned
1h7wA02 19 Dec, 2006 1.10.1060.10 Assigned
1h7wA03 19 Dec, 2006 3.50.50.60 Assigned
1h7wA04 19 Dec, 2006 3.50.50.60 Assigned
1h7wA05 19 Dec, 2006 3.20.20.70 Assigned
1h7wB01 19 Dec, 2006 3.30.70.20 Assigned
1h7wB02 19 Dec, 2006 1.10.1060.10 Assigned
1h7wB03 19 Dec, 2006 3.50.50.60 Assigned
1h7wB04 19 Dec, 2006 3.50.50.60 Assigned
1h7wB05 19 Dec, 2006 3.20.20.70 Assigned
1h7wC01 19 Dec, 2006 3.30.70.20 Assigned
1h7wC02 19 Dec, 2006 1.10.1060.10 Assigned
1h7wC03 19 Dec, 2006 3.50.50.60 Assigned
1h7wC04 19 Dec, 2006 3.50.50.60 Assigned
1h7wC05 19 Dec, 2006 3.20.20.70 Assigned
1h7wD01 20 Dec, 2006 3.30.70.20 Assigned
1h7wD02 20 Dec, 2006 1.10.1060.10 Assigned
1h7wD03 20 Dec, 2006 3.50.50.60 Assigned
1h7wD04 20 Dec, 2006 3.50.50.60 Assigned
1h7wD05 20 Dec, 2006 3.20.20.70 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
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