PDB 1cj1
PDB Information
| PDB | 1CJ1 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic.
J.Med.Chem.
|
| Header | Signaling Protein |
| Released | 1999-04-21 |
| Resolution | 3.000 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Images (25)
1cj1
PDB 1cj1
1cj1A
PDB Chain 1cj1A
1cj1B
PDB Chain 1cj1B
1cj1C
PDB Chain 1cj1C
1cj1D
PDB Chain 1cj1D
1cj1E
PDB Chain 1cj1E
1cj1F
PDB Chain 1cj1F
1cj1G
PDB Chain 1cj1G
1cj1H
PDB Chain 1cj1H
1cj1I
PDB Chain 1cj1I
1cj1J
PDB Chain 1cj1J
1cj1K
PDB Chain 1cj1K
1cj1L
PDB Chain 1cj1L
1cj1A00
CATH Domain 1cj1A00
1cj1B00
CATH Domain 1cj1B00
1cj1C00
CATH Domain 1cj1C00
1cj1D00
CATH Domain 1cj1D00
1cj1E00
CATH Domain 1cj1E00
1cj1F00
CATH Domain 1cj1F00
1cj1G00
CATH Domain 1cj1G00
1cj1H00
CATH Domain 1cj1H00
1cj1I00
CATH Domain 1cj1I00
1cj1J00
CATH Domain 1cj1J00
1cj1K00
CATH Domain 1cj1K00
1cj1L00
CATH Domain 1cj1L00
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Mar, 2006 | Chopped |
| B | 05 Mar, 2006 | Chopped |
| C | 05 Mar, 2006 | Chopped |
| D | 05 Mar, 2006 | Chopped |
| E | 05 Mar, 2006 | Chopped |
| F | 05 Mar, 2006 | Chopped |
| G | 05 Mar, 2006 | Chopped |
| H | 05 Mar, 2006 | Chopped |
| I | 05 Mar, 2006 | Chopped |
| J | 05 Mar, 2006 | Chopped |
| K | 05 Mar, 2006 | Chopped |
| L | 05 Mar, 2006 | Chopped |
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 1cj1A00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1B00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1C00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1D00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1E00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1F00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1G00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1H00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1I00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1J00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1K00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
| 1cj1L00 | 05 Mar, 2006 | 3.30.505.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |
| P62993 | GRB2_HUMAN | Homo sapiens | Growth factor receptor-bound protein 2 |