CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Growth factor receptor-bound protein 2

Enzyme Information

UniProtKB Entries (1)

P62993
GRB2_HUMAN
Homo sapiens
Growth factor receptor-bound protein 2

PDB Structure

PDB 1CJ1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic.
Furet, P., Garcia-Echeverria, C., Gay, B., Schoepfer, J., Zeller, M., Rahuel, J.
J.Med.Chem.