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CATH Superfamily 3.30.870.10

Endonuclease Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Endonuclease Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Polyphosphate kinase
564
3D
 1xdpB03 - 85.4
2
Cardiolipin synthase A
388 - - 64.2
3
Cardiolipin synthase A
370 - - 49.3
4
protein FAM83H isoform X2
367
3D
 5lzkB00 - 96.5
5
Phospholipase
277 - - 78.9
7
Polyphosphate kinase
239
3D
 1xdpB04 - 52.1
6
CDP-diacylglycerol--serine O-phosphatidyltransferase
238 - - 66.8
8
CDP-diacylglycerol--serine O-phosphatidyltransferase
229 - - 66.4
9
Phospholipase
208 - - 75.4
10
Phospholipase
202 - - 80.5
12
Tyrosyl-DNA phosphodiesterase 1
196
3D
 5nwaB01 - 79.3
11
Phospholipase
167 - - 91.5
20
Tyrosyl-DNA phosphodiesterase 1
154
3D
 5nwaB02 - 78.4
13
phospholipase D3 isoform X1
142 - - 76.7
14
Cardiolipin synthase
136 - - 93.7
15
Cardiolipin synthase B
132 - - 51.2
16
Cardiolipin synthase B
122 - - 65.0
17
Phospholipase
120 - - 82.2
18
Phospholipase
118 - - 72.9
19
phospholipase D3 isoform X1
112 - - 82.6
21
Cardiolipin synthase
92 - - 83.3
22
Phospholipase
87 - - 64.6
23
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
78 - - 41.9
24
Cardiolipin synthase C
77 - - 77.9
25
Phospholipase D delta
77 - - 78.9
26
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
73 - - 49.5
27
Phospholipase D
71 - - 74.8
28
Tyrosyl-DNA phosphodiesterase 1
65 - - 98.5
29
Cardiolipin synthase C
60 - - 22.0
30
mitochondrial cardiolipin hydrolase
53
3D
 4ggkA00 - 72.4
31
Tyrosyl-DNA phosphodiesterase 1
41 - - 76.5
32
Phospholipase
41 - - 89.8
33
Phospholipase
33 - - 45.0
34
Phospholipase
33 - - 74.3
35
Phospholipase D domain protein
25 - - 4.9
36
Phospholipase
24 - - 71.9
37
Superfamily I DNA helicase
23 - - 10.9
38
Probable tyrosyl-DNA phosphodiesterase
22 - - 91.5
39
Probable tyrosyl-DNA phosphodiesterase
18 - - 80.6
42
Cardiolipin synthetase domain protein
17 - - 77.6
41
Envelope phospholipase F13
17 - - 9.7
40
Envelope phospholipase F13
17 - - 10.7
43
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
16 - - 10.4
44
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
15 - - 79.5
45
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
15 - - 10.0
47
Probable tyrosyl-DNA phosphodiesterase
14 - - 66.4
48
Phospholipase
14 - - 71.2
46
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
14 - - 83.4
55
Tyrosyl-DNA phosphodiesterase 1
13
3D
 1q32D02 - 2.5
49
Cardiolipin synthetase
12 - - 17.4
52
Polyphosphate kinase
11 - - 0.0
51
Probable tyrosyl-DNA phosphodiesterase
11 - - 75.4
50
Phospholipase
11 - - 54.9
54
Phospholipase
9 - - 16.3
57
DEAD/DEAH box helicase
9 - - 75.2
53
Phospholipase
9 - - 69.7
56
Tyrosine-DNA phosphodiesterase
9 - - 0.0
59
Cardiolipin synthetase, putative
8 - - 34.8
58
Putative cardiolipin synthetase
8 - - 37.4
60
Phospholipase
8 - - 1.9
61
Phospholipase
8 - - 69.1
62
Tyrosyl-DNA phosphodiesterase, putative
7 - - 10.4
63
Nuclease
7 - - 0.0
69
Cardiolipin synthase
6 - - 7.4
65
Phospholipase D, putative
6 - - 9.1
64
Phospholipase D, putative
6 - - 3.8
68
Phospholipase D/Transphosphatidylase
6 - - 17.7
67
Cardiolipin synthase
6 - - 0.0
66
Tyrosyl-DNA phosphodiesterase, putative
6 - - 3.2
70
Phospholipase D family protein
6 - - 14.6
74
Phospholipase D family protein
5 - - 4.9
72
Phospholipase D, putative
5 - - 1.6
78
Uncharacterized protein
5 - - 84.2
77
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
5 - - 0.0
79
Phospholipase D family protein
5 - - 0.0
75
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
5 - - 0.0
73
Phopholipase D-family protein
5 - - 6.2
76
Phospholipase D, putative
5 - - 0.0
71
Tyrosyl-DNA phosphodiesterase
5 - - 33.1
84
Cardiolipin synthase
4 - - 0.0
82
Cardiolipin synthase family enzyme
4 - - 0.0
88
Phospholipase d active site domain-containing protein
4 - - 75.2
92
Phospholipase D
4 - - 1.4
94
Competence protein ComE
4 - - 43.1
87
Cardiolipin synthase
4 - - 0.0
95
Competence protein ComE
4 - - 44.2
89
Phospholipase D
4 - - 7.7
85
Cardiolipin synthase
4 - - 2.9
83
Phospholipase
4 - - 13.3
91
Phospholipase D
4 - - 0.0
90
Phospholipase D
4 - - 0.0
86
Cardiolipin synthase YbhO
4 - - 0.0
80
Probable tyrosyl-DNA phosphodiesterase
4 - - 20.1
81
Tyrosyl-DNA phosphodiesterase
4 - - 31.8
93
Phospholipase D C
4 - - 48.9
97
Uncharacterized protein
3 - - 51.0
98
Uncharacterized protein
3 - - 57.5
101
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
3 - - 0.0
106
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
3 - - 5.8
99
Phospholipase D1-like protein
PLD1
3 - - 18.4
108
Phospholipase D
3 - - 0.0
104
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
3 - - 4.1
103
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
3 - - 2.0
107
Phospholipase D endonuclease superfamily
3 - - 5.6
105
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
3 - - 1.5
100
Tyrosyl-DNA phosphodiesterase 1
3 - - 7.8
109
Phospholipase D
3 - - 0.0
110
PhosphoLipase D
3 - - 13.8
96
Uncharacterized protein
3 - - 60.5
102
Cardiolipin synthase
3 - - 0.7
142
Phospholipase D B
2 - - 16.5
122
Phospholipase D/Transphosphatidylase
2 - - 0.0
140
Cardiolipin synthase B
2 - - 0.0
120
Cardiolipin synthase
2 - - 0.0
129
Tyrosyl-DNA Phosphodiesterase
Tdp1
2 - - 0.0
125
Tyrosyl-DNA Phosphodiesterase
Tdp1
2 - - 0.0
134
Mitochondrial cardiolipin hydrolase
2 - - 0.0
116
Cardiolipin synthase
2 - - 0.0
111
Phospholipase D1-like protein
PLD1
2 - - 16.5
145
Uncharacterized protein
2 - - 39.1
127
AaceriAAR169Cp
2 - - 6.2
138
Uncharacterized protein
2 - - 0.0
114
Phospholipase D A
2 - - 7.4
136
Phospholipase D
2 - - 0.0
131
Uncharacterized protein
2 - - 12.1
143
Phospholipase
2 - - 7.6
118
Phospholipase D/Transphosphatidylase
2 - - 0.0
123
Cardiolipin synthase, putative
2 - - 0.0
128
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
2 - - 2.1
137
Uncharacterized protein
2 - - 0.0
124
Uncharacterized protein
2 - - 0.0
113
Cardiolipin synthetase
2 - - 0.0
135
Uncharacterized protein
2 - - 4.9
144
Uncharacterized protein
2 - - 36.6
133
AGAP006233-PA
2 - - 6.5
141
Cardiolipin synthase B
2 - - 0.0
115
Phospholipase D1
2 - - 0.0
121
Cardiolipin synthetase
2 - - 0.0
117
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
2 - - 0.0
126
YALI0D07590p
2 - - 0.0
132
Phospholipase D family, member 6
2 - - 0.7
119
Phosphatidylcholine-hydrolyzing phospholipase D
PLD
2 - - 0.0
139
Uncharacterized protein
2 - - 0.0
130
Putative endonuclease
2 - - 42.0
112
Tyrosyl-DNA phosphodiesterase 1
2 - - 0.6
189
Uncharacterized protein
1 - - 0.0
193
Uncharacterized protein
1 - - 0.0
180
Uncharacterized protein
1 - - 0.0
153
Uncharacterized protein
1 - - 0.0
170
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
1 - - 0.0
179
Phospholipase D/Transphosphatidylase
1 - - 0.0
197
Uncharacterized protein
1 - - 0.0
157
Uncharacterized protein
1 - - 0.0
182
Predicted protein
1 - - 0.0
149
Phospholipase D superfamily protein
1 - - 0.0
195
Uncharacterized protein
1 - - 0.0
172
Uncharacterized protein
1 - - 0.0
155
Uncharacterized protein
1 - - 0.0
199
Phopholipase D, putative
1 - - 0.0
150
Uncharacterized protein
1 - - 0.0
183
Uncharacterized protein
1 - - 0.0
166
Tyrosyl-DNA phosphodiesterase 1
1 - - 0.0
161
Uncharacterized protein
1 - - 0.0
147
Probable tyrosyl-DNA phosphodiesterase
1 - - 0.0
190
Uncharacterized protein
1 - - 0.0
159
Uncharacterized protein
1 - - 0.0
201
Uncharacterized protein
1 - - 0.0
173
Uncharacterized protein
1 - - 0.0
187
Uncharacterized protein
1 - - 0.0
152
Uncharacterized protein
1 - - 0.0
204
Uncharacterized protein
1 - - 0.0
175
Predicted protein
1 - - 0.0
192
Uncharacterized protein
1 - - 0.0
185
Tyrosyl-DNA phosphodiesterase 1
1 - - 0.0
164
Uncharacterized protein
1 - - 0.0
177
Mitochondrial cardiolipin hydrolase-like Protein
1 - - 0.0
168
Phospholipase D superfamily protein
1 - - 0.0
186
Uncharacterized protein
1 - - 0.0
163
Uncharacterized protein
1 - - 0.0
181
Phospholipase D-related protein
1 - - 0.0
203
Predicted protein
1 - - 0.0
148
Uncharacterized protein
1 - - 0.0
171
Polyphosphate kinase
1 - - 0.0
176
Uncharacterized protein
1 - - 0.0
178
Uncharacterized protein
1 - - 0.0
167
Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
1 - - 0.0
146
Uncharacterized protein
1 - - 0.0
174
Mitochondrial cardiolipin hydrolase
1 - - 0.0
184
Uncharacterized protein
1 - - 0.0
165
Uncharacterized protein
1 - - 0.0
188
Predicted protein
1 - - 0.0
196
Uncharacterized protein
1 - - 0.0
169
Uncharacterized protein
1 - - 0.0
151
AAR169Cp
1 - - 0.0
160
Uncharacterized protein
1 - - 0.0
156
Uncharacterized protein
1 - - 0.0
191
Uncharacterized protein
1 - - 0.0
200
Uncharacterized protein
1 - - 0.0
162
Uncharacterized protein
1 - - 0.0
158
Uncharacterized protein
1 - - 0.0
194
Uncharacterized protein
1 - - 0.0
198
Uncharacterized protein
1 - - 0.0
202
Phospholipase
1 - - 0.0
154
Uncharacterized protein
1 - - 0.0
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