CATH Superfamily 2.10.90.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Bone morphogenetic protein 4	1324	3D	4mplA00	-	98.5
2	Brain-derived neurotrophic factor	736	3D	6ffyC00	-	94.0
3	Bone morphogenetic protein 5	680	3D	1m4uL00	-	85.4
4	Transforming growth factor beta	624	3D	4kv5D00	-	92.7
5	Inhibin beta A chain	578	3D	5hlzF00	-	90.2
6	growth/differentiation factor 8	484	3D	3sekB00	-	93.7
7	Luteinizing hormone beta subunit	448	3D	4mqwH00	-	99.0
9	Vascular endothelial growth factor A	344	3D	6d3oB00	-	81.8
8	Bone morphogenetic protein 3	319	3D	2qcqB00	-	88.4
10	Platelet derived growth factor C	224		-	-	84.3
11	Glycoprotein hormones alpha chain	224	3D	4mqwG00	-	83.5
12	Growth/differentiation factor 9 Predicted	206		-	-	97.0
13	Gremlin	185	3D	5aejD00	-	61.1
15	Glial cell line-derived neurotrophic factor	179	3D	3fubD00	-	72.7
14	Noggin	176	3D	1m4uA01	-	89.4
16	Neuroblastoma suppressor of tumorigenicity 1	140	3D	4x1jA00	-	43.4
17	Platelet derived growth factor subunit A	139	3D	3mjkA00	-	72.0
18	Spatzle 4	138		-	-	95.9
19	Sclerostin domain-containing protein 1	130		-	-	20.4
22	Norrin	121	3D	5bqeB00	-	52.7
20	bone morphogenetic protein 8B	120		-	-	69.6
21	vascular endothelial growth factor D	109		-	-	71.3
23	Platelet-derived growth factor subunit B	99		-	-	70.9
24	Inhibin alpha chain	93		-	-	73.3
25	vascular endothelial growth factor C	88		-	-	72.8
38	Interleukin-17A	85	3D	5nanF00	-	86.5
26	Nodal homolog 3-A	85	3D	4n1dA00	-	83.9
30	Vascular endothelial growth factor B	85	3D	2xacB00	-	92.4
32	Artemin	84	3D	2gyzA00	-	82.6
27	Glycoprotein hormone alpha 2	83		-	-	67.4
28	Left-right determination factor	82		-	-	80.0
29	glycoprotein hormone beta-5	80		-	-	74.7
31	placenta growth factor isoform X2	79	3D	1rv6W00	-	75.1
33	Muellerian-inhibiting factor	69		-	-	88.4
34	Interleukin 17B	64		-	-	36.2
37	neurturin	63	3D	5nmzD00	-	85.4
35	Spz1	61		-	-	91.5
36	Sclerostin	58	3D	2kd3A00	-	33.0
39	growth/differentiation factor 15	49		-	-	89.1
40	Persephin	44		-	-	56.6
42	Cerberus 1 homolog Xenopus laevis	38		-	-	76.4
41	Platelet-derived growth factor beta polypeptide b	38		-	-	70.4
43	Neurotrophin 1, isoform A	29		-	-	38.6
44	Interleukin 17D	25		-	-	60.3
45	DAN domain BMP antagonist family member 5	24		-	-	78.4
56	Protein spaetzle	22	3D	4lxsK00	-	93.1
46	Interleukin 17C	19		-	-	32.7
47	Left-right determination factor	19		-	-	83.9
49	Glycoprotein hormone alpha 2	18		-	-	93.2
53	PDGF-and VEGF-related factor 3	18		-	-	81.6
51	Uncharacterized protein, isoform A	18		-	-	82.0
50	Nerve growth factor beta polypeptide	18		-	-	35.7
48	Glycoprotein hormone beta 5	18		-	-	70.5
52	Bone morphogenetic protein	18		-	-	74.4
54	Bursicon	16		-	-	37.2
55	Placenta growth factor	15		-	-	80.4
57	Interleukin 17E	13		-	-	31.3
58	Maverick	11		-	-	78.9
60	Spatzle 6	10		-	-	3.5
59	CRE-TIG-2 protein	10		-	-	54.0
61	Inhibin alpha chain	10		-	-	69.2
62	GK21666	9		-	-	15.7
65	Brain-derived neurotrophic factor	8		-	-	2.5
64	Glycoprotein hormone alpha 2	8		-	-	19.9
63	Glycoprotein hormone beta 5	8		-	-	24.9
69	noggin	7		-	-	14.0
66	Nerve growth factor a beta polypeptide	7		-	-	39.4
67	Prothoracicotropic hormone, isoform F	7		-	-	13.6
68	AGAP000342-PA	7		-	-	18.3
72	Predicted protein	6		-	-	88.3
70	CRE-UNC-129 protein	6		-	-	10.6
71	PDGF-and VEGF-related factor 1, isoform B	6		-	-	5.7
75	Follicle stimulating hormone beta	5		-	-	89.1
73	Beadex/dlmo protein	5		-	-	10.0
74	Interleukin cytokine-related protein 17.1	5		-	-	15.6
103	Bone morphogenetic protein 16	4	3D	1reuA00	-	39.7
86	Vascular endothelial growth factor c	4		-	-	5.8
77	TransformIng Growth factor beta family	4		-	-	32.2
80	Nodal homolog 4-A	4		-	-	6.9
79	Uncharacterized protein	4		-	-	74.5
82	Cerberus	4		-	-	9.6
85	Uncharacterized protein	4		-	-	8.0
87	Bone morphogenetic protein 5	4		-	-	13.1
76	Interleukin 17c	4		-	-	4.7
88	Inhibin beta B chain	4		-	-	68.0
84	Gonadal soma derived factor variant 2	4		-	-	0.0
83	Neurturin	4		-	-	2.4
78	Putative bursicon beta	4		-	-	33.8
81	DAN domain family member 5	4		-	-	4.4
97	Uncharacterized protein	3		-	-	0.0
89	PDGF/VEGF growth factor related	3		-	-	15.4
92	GM13635	3		-	-	13.1
95	Transforming growth factor beta-3	3		-	-	36.4
90	transforming growth factor beta superfamily signaling ligand isoform X1	3		-	-	7.0
96	Uncharacterized protein	3		-	-	0.0
93	AGAP000859-PA	3		-	-	11.4
91	Uncharacterized protein	3		-	-	9.6
98	Uncharacterized protein	3		-	-	0.0
94	Transforming growth factor beta	3		-	-	17.1
119	Artemin	2		-	-	0.0
115	Uncharacterized protein	2		-	-	0.0
135	MUC5B	2		-	-	13.1
120	Brain-derived neurotrophic factor	2		-	-	1.5
104	Uncharacterized protein	2		-	-	38.9
102	Uncharacterized protein	2		-	-	38.0
126	Growth/differentiation factor 8	2		-	-	0.0
124	Bone morphogenetic protein 7	2		-	-	0.0
99	Uncharacterized protein	2		-	-	4.6
100	Putative glycoprotein hormone-beta5	2		-	-	32.4
106	VEGF183 protein, putative	2		-	-	39.7
122	Prepro-neurotrophin	2		-	-	1.9
118	Vascular endothelial growth factor-like protein	2		-	-	0.0
117	Uncharacterized protein	2		-	-	0.0
131	Noggin-3	2		-	-	0.0
111	Platelet-derived growth factor subunit B	2		-	-	3.7
123	Interleukin 17 isoform A	2		-	-	10.4
129	Uncharacterized protein	2		-	-	0.0
101	Glycoprotein hormone alpha 2	2		-	-	34.6
125	Activin B	2		-	-	1.9
108	DAN domain family, member 5	2		-	-	2.1
107	Protein CBR-DAF-7	2		-	-	2.0
110	Unc-129 protein	2		-	-	0.0
116	Uncharacterized protein	2		-	-	0.0
130	Noggin	2		-	-	0.0
132	Uncharacterized protein	2		-	-	0.0
114	Uncharacterized protein	2		-	-	0.0
112	Uncharacterized protein	2		-	-	0.0
134	Vascular endothelial growth factor Bb	2		-	-	41.5
127	Predicted protein	2		-	-	0.0
128	Uncharacterized protein	2		-	-	4.5
105	Uncharacterized protein	2		-	-	43.0
133	Uncharacterized protein Fragment	2		-	-	42.2
109	Nodal homolog 2-A	2		-	-	0.0
113	Uncharacterized protein	2		-	-	0.0
121	Protein trunk	2		-	-	0.9
164	Uncharacterized protein	1		-	-	0.0
139	Bone morphogenetic protein, putative	1		-	-	0.0
162	Glycoprotein hormones alpha chain	1		-	-	0.0
170	Bone morphogenetic protein 2	1		-	-	0.0
141	Uncharacterized protein	1		-	-	0.0
176	Uncharacterized protein	1		-	-	0.0
148	Uncharacterized protein	1		-	-	0.0
150	Uncharacterized protein	1		-	-	0.0
147	Uncharacterized protein	1		-	-	0.0
163	Growth differential factor 9	1		-	-	0.0
156	Glycoprotein hormone beta, putative	1		-	-	0.0
154	Nodal-related protein 1	1		-	-	0.0
152	Uncharacterized protein	1		-	-	0.0
138	Uncharacterized protein	1		-	-	0.0
173	Predicted protein	1		-	-	0.0
137	Uncharacterized protein	1		-	-	0.0
174	Uncharacterized protein	1		-	-	0.0
149	Uncharacterized protein	1		-	-	0.0
172	Transforming growth factor, beta 2	1		-	-	0.0
145	Uncharacterized protein	1		-	-	0.0
160	Uncharacterized protein	1		-	-	0.0
153	Predicted protein	1		-	-	0.0
166	Uncharacterized protein	1		-	-	0.0
159	Glycoprotein hormone beta 5	1		-	-	0.0
155	Vascular endothelial growth factor B	1		-	-	0.0
167	Uncharacterized protein	1		-	-	0.0
168	Bone morphogenetic protein 8B-like protein	1		-	-	0.0
143	transforming growth factor beta superfamily signaling ligand isoform X1	1		-	-	0.0
179	Uncharacterized protein	1		-	-	0.0
144	Uncharacterized protein	1		-	-	0.0
142	Transforming growth factor beta superfamily signaling ligand	1		-	-	0.0
136	Uncharacterized protein	1		-	-	0.0
175	Uncharacterized protein	1		-	-	0.0
161	Uncharacterized protein	1		-	-	0.0
169	Uncharacterized protein	1		-	-	0.0
157	Otogelin	1		-	-	0.0
165	Uncharacterized protein	1		-	-	0.0
140	Uncharacterized protein	1		-	-	0.0
158	Uncharacterized protein	1		-	-	0.0
146	Uncharacterized protein	1		-	-	0.0
171	Transforming growth factor beta	1		-	-	0.0
178	Uncharacterized protein	1		-	-	0.0
177	Uncharacterized protein	1		-	-	0.0
151	Invected	1		-	-	0.0

Network disruptions

CATH Superfamily 2.10.90.10

Cystine-knot cytokines

Functional Families

Browse Functional Families