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Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
3072 - - 98.4
2
1202
3D
1hciB01 - 82.6
3
1199
3D
1hciB04 - 95.0
4
1153
3D
1quuA01 - 89.7
5
1141
3D
1quuA02 - 96.7
6
1131 - - 89.3
7
1015
3D
2spcB00 - 99.7
8
843 - - 100.0
9
841
3D
2iakA01 - 93.2
10
786 - - 99.6
11
772
3D
3lbxB02 - 98.7
12
731 - - 71.3
13
665
3D
3fb2B01 - 99.2
14
661 - - 79.3
15
639 - - 50.3
16
629 - - 82.4
17
609
3D
1u5pA01 - 98.7
18
601
3D
3lbxB01 - 94.5
19
585
3D
3kbuB00 - 94.4
20
580
3D
1u4qB03 - 95.8
21
572 - - 73.3
22
557 - - 74.5
23
551 - - 81.5
24
548 - - 60.3
25
544 - - 71.2
26
521 - - 68.2
28
505
3D
1s35A01 - 91.4
27
504 - - 79.1
29
500 - - 93.1
30
479 - - 97.2
31
479 - - 85.5
32
469 - - 70.7
33
468 - - 97.1
34
460 - - 78.7
35
430 - - 77.1
36
418
3D
2odvA01 - 71.6
37
404
3D
1u5pA02 - 70.0
38
384 - - 65.1
41
378 - - 72.2
39
378 - - 94.6
40
378 - - 66.8
42
376 - - 78.1
43
372 - - 82.7
44
366 - - 78.7
46
365 - - 49.2
45
365 - - 76.2
47
362 - - 81.1
48
361 - - 58.5
49
356
3D
1s35A02 - 95.7
50
341 - - 87.6
51
337 - - 66.3
52
337 - - 71.2
53
336 - - 89.7
54
336 - - 54.7
56
335 - - 93.0
55
335 - - 74.2
57
333 - - 55.0
58
332 - - 64.9
59
329 - - 87.8
60
328 - - 77.4
61
327 - - 69.5
62
323 - - 62.8
65
321
3D
5j1gB00 - 84.1
63
320 - - 65.0
64
319 - - 60.8
66
317 - - 38.5
67
315 - - 76.1
68
312 - - 90.8
69
310 - - 58.2
70
303 - - 89.7
71
300 - - 56.0
75
293
3D
3uunB00 - 91.0
72
292 - - 68.7
73
290 - - 79.5
76
288
3D
2odvA02 - 65.6
74
287 - - 66.8
78
284 - - 77.5
77
284 - - 75.6
79
276 - - 54.3
80
273 - - 25.7
81
273 - - 94.0
82
269 - - 91.8
83
266 - - 73.4
84
258 - - 64.6
86
254 - - 12.8
85
254 - - 79.5
87
252 - - 79.1
88
251 - - 71.8
89
250 - - 65.4
90
248 - - 75.8
92
247 - - 94.9
91
247 - - 78.9
93
246 - - 83.8
94
239 - - 72.6
95
235 - - 97.0
96
231 - - 50.4
97
229 - - 64.6
98
220 - - 76.8
99
199 - - 89.6
100
198 - - 55.8
101
186 - - 65.2
102
179 - - 74.1
103
177 - - 67.2
104
176 - - 49.7
105
173 - - 72.9
106
172 - - 86.0
107
166 - - 17.9
108
161 - - 76.9
110
160 - - 37.3
109
160 - - 96.7
112
159 - - 89.1
111
159 - - 60.1
113
157 - - 56.8
114
156 - - 89.5
115
151 - - 55.5
116
148 - - 76.5
117
147 - - 61.1
118
147 - - 74.7
119
147 - - 66.7
120
140 - - 44.6
121
138 - - 86.0
123
136
3D
3r6nB01 - 74.1
122
135 - - 71.5
124
133 - - 39.6
125
132 - - 79.2
127
126 - - 93.3
126
126 - - 64.4
128
123 - - 41.4
129
119 - - 36.5
130
118 - - 83.1
131
117 - - 72.5
135
116 - - 95.9
133
116 - - 61.7
134
116 - - 64.4
132
116 - - 64.8
138
114 - - 91.9
139
114 - - 65.4
136
114 - - 35.5
137
114 - - 81.6
140
110 - - 76.1
141
104 - - 75.8
142
102 - - 82.7
143
101 - - 75.8
144
100 - - 55.7
145
98 - - 90.2
146
92 - - 66.4
147
90 - - 44.7
148
88 - - 41.0
151
86 - - 24.1
150
86 - - 34.3
149
86 - - 70.8
152
84 - - 95.3
153
81 - - 87.6
155
80 - - 72.1
154
80 - - 47.8
156
78 - - 72.8
157
77 - - 55.8
158
75 - - 71.5
159
74 - - 59.6
160
74 - - 83.2
161
73 - - 8.6
163
72 - - 72.0
162
72 - - 57.4
164
71 - - 60.3
166
70 - - 59.2
165
70 - - 32.5
168
69 - - 35.6
167
69 - - 49.5
170
68 - - 70.9
169
68 - - 67.1
171
68 - - 97.8
172
67 - - 78.7
173
67 - - 85.7
174
66 - - 92.3
175
65 - - 25.7
177
64 - - 58.2
176
64 - - 56.9
178
63 - - 84.7
179
62 - - 32.6
181
59 - - 69.1
180
59 - - 86.6
183
58 - - 57.4
182
58 - - 58.6
184
58 - - 55.7
185
57 - - 63.1
186
56 - - 64.2
189
55 - - 60.1
188
55 - - 69.9
187
55 - - 32.8
190
54 - - 70.7
192
52 - - 66.4
191
52 - - 82.7
193
52 - - 41.8
194
51 - - 32.8
195
51 - - 85.8
196
49 - - 17.3
197
48 - - 23.3
198
48 - - 22.6
199
47 - - 14.4
200
46 - - 42.7
202
46 - - 19.0
201
46 - - 18.4
204
45 - - 27.9
205
45 - - 15.2
203
45 - - 20.4
207
43 - - 26.3
206
43 - - 49.2
210
42 - - 74.9
209
42 - - 16.5
208
42 - - 14.2
212
41 - - 47.4
214
41 - - 88.1
213
41 - - 48.9
211
41 - - 51.4
217
40 - - 44.6
215
40 - - 32.1
216
40 - - 51.1
219
40 - - 19.2
218
40 - - 36.3
220
39 - - 16.1
222
39 - - 55.0
221
39 - - 33.6
224
38 - - 66.1
225
38 - - 92.5
223
38 - - 8.8
227
37 - - 10.5
228
37 - - 6.9
229
37 - - 97.3
226
37 - - 42.4
231
36 - - 63.9
230
36 - - 80.5
233
35 - - 31.4
232
35 - - 74.1
235
34 - - 24.6
234
34 - - 78.4
236
33 - - 52.0
238
33 - - 29.1
237
33 - - 46.4
240
32 - - 44.8
239
32 - - 33.4
244
31 - - 17.0
242
31 - - 43.4
245
31 - - 15.1
243
31 - - 73.4
241
31 - - 36.5
247
30 - - 87.3
248
30 - - 43.4
246
30 - - 38.8
251
29 - - 29.4
252
29 - - 34.7
250
29 - - 47.8
249
29 - - 37.2
256
28 - - 22.1
253
28 - - 92.3
255
28 - - 31.2
254
28 - - 41.1
257
28 - - 5.2
258
27 - - 53.0
261
27 - - 10.2
259
27 - - 94.6
262
27 - - 19.4
260
27 - - 91.9
266
26 - - 21.5
265
26 - - 9.9
263
26 - - 15.7
264
26 - - 25.6
267
26 - - 67.7
269
25 - - 6.3
270
25 - - 8.4
268
25 - - 8.3
271
25 - - 48.6
274
24 - - 30.1
272
24 - - 64.4
273
24 - - 31.0
275
24 - - 35.4
277
23 - - 95.3
278
23 - - 11.5
276
23 - - 36.2
281
22 - - 43.9
282
22 - - 83.6
280
22 - - 50.6
279
22 - - 76.4
286
21 - - 64.5
283
21 - - 43.7
285
21 - - 35.6
284
21 - - 33.2
288
20 - - 10.8
289
20 - - 63.0
290
20 - - 13.7
287
20 - - 43.8
294
19 - - 52.2
292
19 - - 45.6
300
19 - - 82.2
297
19 - - 21.5
291
19 - - 48.1
298
19 - - 24.1
296
19 - - 73.8
299
19 - - 76.0
293
19 - - 85.8
295
19 - - 39.2
307
18 - - 87.8
304
18 - - 25.7
302
18 - - 53.0
303
18 - - 16.3
305
18 - - 29.0
308
18 - - 53.1
301
18 - - 41.1
306
18 - - 58.2
317
17 - - 2.4
310
17 - - 43.1
314
17 - - 21.0
312
17 - - 33.6
315
17 - - 8.1
313
17 - - 43.0
311
17 - - 30.2
316
17 - - 12.2
309
17 - - 80.0
320
16 - - 17.4
327
16 - - 7.6
322
16 - - 19.9
324
16 - - 10.2
323
16 - - 12.3
325
16 - - 17.6
326
16 - - 12.7
318
16 - - 70.7
319
16 - - 59.7
321
16 - - 15.8
340
15 - - 34.1
335
15 - - 12.3
333
15 - - 21.3
331
15 - - 29.7
338
15 - - 84.5
339
15 - - 40.7
336
15 - - 19.7
337
15 - - 20.0
330
15 - - 22.0
334
15 - - 12.5
329
15 - - 68.8
332
15 - - 22.0
328
15 - - 63.0
347
14 - - 20.3
342
14 - - 38.4
344
14 - - 7.8
343
14 - - 15.6
345
14 - - 3.8
346
14 - - 6.2
350
14 - - 51.7
349
14 - - 12.5
341
14 - - 26.1
348
14 - - 25.3
359
13 - - 48.9
356
13 - - 16.8
358
13 - - 10.1
351
13 - - 37.6
355
13 - - 71.4
353
13 - - 21.8
352
13 - - 19.4
354
13 - - 30.7
357
13 - - 8.9
361
12 - - 60.9
363
12 - - 20.9
362
12 - - 16.8
360
12 - - 46.2
370
11 - - 6.3
368
11 - - 16.9
366
11 - - 22.5
369
11 - - 15.5
372
11 - - 82.5
374
11 - - 64.5
365
11 - - 18.2
364
11 - - 25.4
373
11 - - 47.1
367
11 - - 9.3
371
11 - - 11.7
386
10 - - 47.8
377
10 - - 33.8
381
10 - - 4.8
385
10 - - 15.8
383
10 - - 9.9
375
10 - - 87.9
382
10 - - 3.4
384
10 - - 5.9
379
10 - - 11.8
380
10 - - 12.2
376
10 - - 26.6
378
10 - - 18.8
389
9 - - 58.2
392
9 - - 40.6
402
9 - - 18.3
388
9 - - 16.2
394
9 - - 70.8
404
9 - - 16.5
400
9 - - 11.0
390
9 - - 28.5
397
9 - - 18.7
399
9 - - 1.9
396
9 - - 1.4
391
9 - - 12.7
401
9 - - 22.8
398
9 - - 2.5
405
9 - - 17.1
395
9 - - 43.9
393
9 - - 18.2
403
9 - - 83.2
387
9 - - 8.7
412
8 - - 0.5
414
8 - - 20.1
410
8 - - 7.8
407
8 - - 47.5
417
8 - - 44.8
409
8 - - 15.6
416
8 - - 70.1
406
8 - - 24.7
408
8 - - 65.2
411
8 - - 11.2
413
8 - - 23.0
415
8 - - 3.0
424
7 - - 2.6
422
7 - - 18.5
427
7 - - 59.5
420
7 - - 11.8
421
7 - - 13.3
428
7 - - 18.4
419
7 - - 66.4
429
7 - - 57.8
426
7 - - 12.3
418
7 - - 17.5
425
7 - - 8.5
423
7 - - 22.7
436
6 - - 15.9
439
6 - - 13.8
472
6
3D
3edvB01 - 16.9
438
6 - - 9.7
442
6 - - 41.6
431
6 - - 80.2
433
6 - - 9.2
435
6 - - 14.8
440
6 - - 1.2
432
6 - - 11.4
441
6 - - 2.4
434
6 - - 12.2
430
6 - - 51.7
437
6 - - 4.6
444
5 - - 6.1
447
5 - - 36.3
448
5 - - 42.7
449
5 - - 42.0
450
5 - - 56.2
446
5 - - 3.0
445
5 - - 15.1
443
5 - - 3.4
465
4 - - 6.6
474
4 - - 0.6
463
4 - - 0.0
453
4 - - 70.3
455
4 - - 0.0
469
4 - - 9.9
451
4 - - 59.1
477
4 - - 26.4
458
4 - - 1.9
466
4 - - 0.0
468
4 - - 14.2
456
4 - - 3.8
470
4 - - 13.5
461
4 - - 0.0
459
4 - - 13.4
460
4 - - 8.1
478
4 - - 64.9
457
4 - - 8.7
471
4 - - 11.1
476
4 - - 14.5
467
4 - - 0.9
479
4 - - 56.3
462
4 - - 7.0
454
4 - - 68.5
473
4 - - 0.0
464
4 - - 7.2
452
4 - - 47.2
475
4 - - 12.7
512
3 - - 33.1
502
3 - - 14.0
497
3 - - 0.5
490
3 - - 45.0
483
3 - - 12.5
504
3 - - 13.6
485
3 - - 25.0
510
3 - - 45.0
481
3 - - 22.9
494
3 - - 1.1
488
3 - - 33.9
500
3 - - 11.5
507
3 - - 10.0
486
3 - - 57.5
492
3 - - 29.8
489
3 - - 23.4
509
3 - - 29.1
487
3 - - 36.0
506
3 - - 0.0
493
3 - - 4.8
501
3 - - 0.7
508
3 - - 7.5
480
3 - - 17.8
495
3 - - 7.8
511
3 - - 33.7
505
3 - - 0.0
498
3 - - 1.0
491
3 - - 10.6
503
3 - - 1.2
484
3 - - 6.3
482
3 - - 24.6
496
3 - - 0.0
499
3 - - 7.5
604
2 - - 3.5
565
2 - - 2.2
544
2 - - 8.4
524
2 - - 0.0
536
2 - - 17.4
574
2 - - 0.0
539
2 - - 8.2
563
2 - - 4.9
622
2 - - 27.5
597
2 - - 0.0
614
2 - - 40.2
624
2 - - 36.0
590
2 - - 9.1
612
2 - - 0.0
583
2 - - 1.0
572
2 - - 0.0
553
2 - - 29.8
538
2 - - 0.0
522
2 - - 1.3
514
2 - - 1.5
555
2 - - 27.4
542
2 - - 0.0
602
2 - - 5.1
585
2 - - 0.6
531
2 - - 0.0
569
2 - - 10.4
533
2 - - 0.0
527
2 - - 0.0
547
2 - - 0.0
607
2 - - 1.0
594
2 - - 0.0
617
2 - - 11.4
535
2 - - 6.9
581
2 - - 2.0
620
2 - - 0.0
551
2 - - 0.0
577
2 - - 0.0
558
2 - - 0.0
566
2 - - 0.0
588
2 - - 0.0
568
2 - - 8.6
570
2 - - 0.0
556
2 - - 27.8
586
2 - - 0.6
610
2 - - 0.0
592
2 - - 6.1
561
2 - - 0.0
600
2 - - 0.0
540
2 - - 0.0
517
2 - - 0.0
589
2 - - 1.4
520
2 - - 1.0
559
2 - - 0.0
548
2 - - 41.9
608
2 - - 28.7
521
2 - - 0.0
532
2 - - 0.0
528
2 - - 0.0
516
2 - - 0.0
541
2 - - 7.0
601
2 - - 0.0
611
2 - - 6.0
519
2 - - 0.4
587
2 - - 1.1
560
2 - - 2.1
578
2 - - 1.6
557
2 - - 31.0
571
2 - - 1.2
618
2 - - 9.7
549
2 - - 39.7
616
2 - - 43.9
593
2 - - 5.0
609
2 - - 1.8
580
2 - - 1.9
550
2 - - 0.0
621
2 - - 35.8
576
2 - - 4.3
567
2 - - 8.3
529
2 - - 0.0
595
2 - - 0.0
526
2 - - 0.0
534
2 - - 0.7
579
2 - - 0.5
518
2 - - 0.0
619
2 - - 1.1
606
2 - - 0.0
546
2 - - 0.0
513
2 - - 0.0
530
2 - - 0.6
598
2 - - 1.3
623
2 - - 39.8
515
2 - - 0.0
554
2 - - 26.6
562
2 - - 0.0
584
2 - - 0.5
591
2 - - 0.0
605
2 - - 0.8
573
2 - - 1.3
545
2 - - 36.5
552
2 - - 53.7
564
2 - - 2.6
582
2 - - 0.0
525
2 - - 0.0
596
2 - - 1.8
613
2 - - 0.0
575
2 - - 0.0
543
2 - - 0.0
603
2 - - 1.6
599
2 - - 7.1
537
2 - - 0.0
615
2 - - 2.2
523
2 - - 0.0
683
1 - - 0.0
851
1 - - 0.0
881
1 - - 0.0
653
1 - - 0.0
797
1 - - 0.0
835
1 - - 0.0
672
1 - - 0.0
894
1 - - 0.0
800
1 - - 0.0
888
1 - - 0.0
702
1 - - 0.0
866
1 - - 0.0
877
1 - - 0.0
858
1 - - 0.0
763
1 - - 0.0
739
1 - - 0.0
690
1 - - 0.0
774
1 - - 0.0
736
1 - - 0.0
827
1 - - 0.0
724
1 - - 0.0
642
1 - - 0.0
833
1 - - 0.0
869
1 - - 0.0
655
1 - - 0.0
712
1 - - 0.0
631
1 - - 0.0
810
1 - - 0.0
685
1 - - 0.0
744
1 - - 0.0
765
1 - - 0.0
847
1 - - 0.0
638
1 - - 0.0
636
1 - - 0.0
840
1 - - 0.0
742
1 - - 0.0
755
1 - - 0.0
731
1 - - 0.0
785
1 - - 0.0
644
1 - - 0.0
722
1 - - 0.0
665
1 - - 0.0
859
1 - - 0.0
738
1 - - 0.0
820
1 - - 0.0
889
1 - - 0.0
817
1 - - 0.0
714
1 - - 0.0
704
1 - - 0.0
783
1 - - 0.0
886
1 - - 0.0
807
1 - - 0.0
753
1 - - 0.0
697
1 - - 0.0
772
1 - - 0.0
856
1 - - 0.0
870
1 - - 0.0
868
1 - - 0.0
861
1 - - 0.0
892
1 - - 0.0
663
1 - - 0.0
639
1 - - 0.0
790
1 - - 0.0
674
1 - - 0.0
692
1 - - 0.0
766
1 - - 0.0
758
1 - - 0.0
777
1 - - 0.0
863
1 - - 0.0
874
1 - - 0.0
839
1 - - 0.0
700
1 - - 0.0
788
1 - - 0.0
802
1 - - 0.0
661
1 - - 0.0
781
1 - - 0.0
735
1 - - 0.0
794
1 - - 0.0
656
1 - - 0.0
670
1 - - 0.0
668
1 - - 0.0
751
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