View in Gene3D

CATH Superfamily 1.20.1740.10

Amino acid/polyamine transporter I

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Amino acid/polyamine transporter I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 19: Tryptophan permease TnaB

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
High-affinity tryptophan transmembrane transporter activity GO:0005300
Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
 40 P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA)
(30 more)
Symporter activity GO:0015293
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
 40 P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA)
(30 more)
Active transmembrane transporter activity GO:0022804
Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
 40 P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP) P0AAD2 (/EXP)
(30 more)
Symporter activity GO:0015293
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
 11 P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP) P23173 (/IMP)
(1 more)
L-tryptophan transmembrane transporter activity GO:0015196
Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.
 4 Q9KN06 (/ISS) Q9KN06 (/ISS) Q9KN06 (/ISS) Q9KN06 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amino acid transmembrane transport GO:0003333
The process in which an amino acid is transported across a membrane.
 51 P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA)
(41 more)
Tryptophan transport GO:0015827
The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 4 Q9KN06 (/ISS) Q9KN06 (/ISS) Q9KN06 (/ISS) Q9KN06 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 51 P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA)
(41 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 40 P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA) P0AAD2 (/IDA)
(30 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...