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CATH Superfamily 1.20.1250.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Interferon alpha
277
3D
 4z5rX00 - 97.1
3
Prolactin
177
3D
 3npzA00 - 88.6
2
Growth hormone
173 - - 72.0
4
Kit ligand
149
3D
 2o27B00 - 81.1
6
Interleukin-6
123
3D
 5fucB00 - 93.3
7
Interferon gamma
122
3D
 6e3lB00 - 96.5
10
Macrophage colony-stimulating factor 1
118
3D
 3uf5B00 - 71.6
5
cardiotrophin-like cytokine factor 1
115 - - 79.8
8
Leptin
105
3D
 1ax8A00 - 76.7
11
Interleukin-10
105
3D
 4x51B00 - 83.6
25
Interleukin-2
102
3D
 5utzI00 - 62.7
12
Growth hormone 1
96
3D
 3hhrA00 - 81.9
9
Growth hormone
93 - - 80.1
14
Interleukin-4
92
3D
 5fhxA00 - 94.4
13
Erythropoietin
72
3D
 1eerA00 - 73.5
21
Granulocyte colony-stimulating factor
72
3D
 5gw9D00 - 86.2
24
Interleukin-23 subunit alpha
69
3D
 5njdL00 - 73.3
15
thrombopoietin isoform X2
67
3D
 1v7nZ00 - 68.7
18
leukemia inhibitory factor
65
3D
 1lkiA00 - 83.0
16
Fms-related tyrosine kinase 3 ligand
64
3D
 1eteD00 - 84.7
17
Interleukin 11
61
3D
 4mhlA00 - 94.4
19
Interleukin 20
59
3D
 4dohC00 - 78.3
28
Granulocyte-macrophage colony-stimulating factor
57
3D
 6bfsC00 - 81.5
20
Interleukin-12 subunit alpha
56
3D
 3hmxB00 - 65.2
22
ciliary neurotrophic factor
55
3D
 1cnt400 - 74.5
29
Interleukin-13
51
3D
 5l6yC00 - 66.6
23
Cardiotrophin-2
50 - - 88.0
26
Interferon beta
45
3D
 3wcyI00 - 96.0
32
Interleukin-22
40
3D
 3q1sI00 - 47.1
27
Cardiotrophin 1
36 - - 65.3
34
Interleukin-5
35
3D
 3b5kB00 - 46.8
30
Type I interferon
35
3D
 3pivB00 - 78.2
31
Oncostatin M
30
3D
 1evsA00 - 70.7
33
Interferon epsilon
26 - - 76.9
35
Interleukin-27 subunit alpha
25 - - 72.1
36
Growth hormone d15
24 - - 87.5
37
Prolactin
24 - - 59.1
38
Interleukin 24
23 - - 42.8
39
Placental prolactin-related protein 2
23 - - 79.7
41
Growth hormone d20
18 - - 91.8
40
Interleukin 26
18 - - 16.2
42
Somatolactin alpha
17 - - 63.9
43
Growth hormone d5
16 - - 72.0
44
Interferon kappa
15 - - 82.6
45
Interferon C
14 - - 25.1
48
Kit ligand b
12 - - 78.1
47
Growth hormone d21
12 - - 67.1
46
Interferon alpha
12 - - 37.2
49
Interferon gamma
11 - - 77.1
80
Interferon gamma
10
3D
 1rfbB00 - 33.2
50
Chorionic somatomammotropin hormone 1
9
3D
 1f6fA00 - 26.2
52
Interleukin-3
8 - - 10.3
51
Type I interferon
8 - - 12.6
56
Colony-stimulating factor 1b
macrophage
7 - - 92.4
55
Predicted gene 13275
7 - - 13.4
54
Prolactin 2
7 - - 51.9
57
Interferon B
7 - - 8.3
53
Growth hormone 2
7 - - 31.1
62
Uncharacterized protein
6 - - 11.5
61
Prolactin-2B1
6 - - 18.1
60
Uncharacterized protein
6 - - 69.8
58
Leptin A1
6 - - 15.4
59
Growth hormone d13
6 - - 25.7
63
Chorionic somatomammotropin hormone
6 - - 10.2
71
Interleukin 4
5 - - 0.0
66
Prolactin-3C1
5 - - 26.8
70
Uncharacterized protein
5 - - 3.8
65
Prolactin, gene 2
5 - - 28.4
64
Growth hormone d23
5 - - 19.1
67
Interleukin-3
5 - - 53.7
69
Interleukin-6
5 - - 9.1
68
Ciliary neurotrophic factor
5 - - 10.2
74
Interleukin-3
4 - - 36.5
77
Colony-stimulating factor 1
4 - - 0.8
76
Erythropoietin
4 - - 0.0
72
Prolactin family 3, subfamily a, member 1
4 - - 35.2
75
Uncharacterized protein
4 - - 69.3
73
Growth hormone d24
4 - - 15.2
79
4 - - 3.0
78
Kit ligand
4 - - 8.1
82
Interleukin-22
3 - - 12.7
85
Colony stimulating factor 2
Granulocyte-macrophage
3 - - 1.0
86
3 - - 4.2
81
3 - - 14.9
84
3 - - 40.6
83
Interferon kappa
3 - - 25.1
101
2 - - 8.9
106
2 - - 1.6
96
2 - - 4.7
92
2 - - 0.0
95
2 - - 0.0
102
2 - - 4.8
103
2 - - 8.0
87
2 - - 9.9
91
2 - - 40.3
94
2 - - 1.7
90
2 - - 7.5
97
2 - - 7.6
88
2 - - 10.0
89
2 - - 21.9
99
2 - - 0.0
108
2 - - 0.6
100
2 - - 0.0
98
2 - - 3.1
93
2 - - 0.0
105
Leptin
2 - - 1.5
109
2 - - 0.0
107
2 - - 4.1
104
2 - - 0.8
116
1 - - 0.0
111
1 - - 0.0
146
1 - - 0.0
141
1 - - 0.0
130
1 - - 0.0
142
1 - - 0.0
123
1 - - 0.0
112
1 - - 0.0
138
1 - - 0.0
113
1 - - 0.0
135
1 - - 0.0
122
1 - - 0.0
143
1 - - 0.0
134
1 - - 0.0
137
1 - - 0.0
126
1 - - 0.0
121
1 - - 0.0
139
1 - - 0.0
124
1 - - 0.0
127
1 - - 0.0
131
1 - - 0.0
136
1 - - 0.0
129
1 - - 0.0
125
1 - - 0.0
118
1 - - 0.0
132
1 - - 0.0
140
1 - - 0.0
110
1 - - 0.0
120
1 - - 0.0
133
1 - - 0.0
115
1 - - 0.0
128
1 - - 0.0
145
1 - - 0.0
119
1 - - 0.0
114
1 - - 0.0
144
1 - - 0.0
117
1 - - 0.0
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