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Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
621
3D
3t3zD00 - 90.1
2
427
3D
6cizD00 - 96.5
18
383
3D
5de9B00 - 99.3
3
315 - - 93.0
4
311
3D
5tfuD00 - 95.5
40
301
3D
6h1sB00 - 94.9
6
224
3D
3k9yB00 - 92.3
5
221 - - 90.6
7
209 - - 96.4
15
201
3D
4zgxL00 - 94.8
8
196 - - 92.6
9
191 - - 88.1
10
190 - - 93.5
11
185 - - 97.9
12
173 - - 94.6
13
171 - - 74.2
14
154 - - 86.5
16
147 - - 90.1
17
141 - - 94.8
24
137
3D
3dskB00 - 93.7
19
131 - - 96.3
20
128 - - 93.0
21
126 - - 95.7
22
125 - - 95.7
23
123 - - 96.8
25
prostacyclin
122
3D
3b6hB00 - 95.1
27
120
3D
3ld6B00 - 72.4
26
118 - - 95.0
31
112
3D
4j14A00 - 95.6
32
110
3D
5jl9A00 - 77.8
30
108
3D
3dl9B00 - 75.2
28
108 - - 93.6
29
107 - - 91.4
34
101
3D
3v8dB00 - 76.7
33
99
3D
4ze2A01 - 91.7
238
96
3D
4ruiF00 - 53.5
96
95
3D
6mjmA00 - 46.7
35
87 - - 95.7
37
85 - - 96.3
36
85 - - 91.6
38
84 - - 89.1
39
83 - - 94.7
41
78 - - 72.0
42
76 - - 96.9
43
75 - - 91.9
44
71 - - 87.6
49
70
3D
4y8wC00 - 94.9
45
70 - - 76.5
46
67 - - 74.8
47
66 - - 92.1
48
63 - - 85.2
142
59
3D
5op9A00 - 8.8
50
55 - - 94.1
51
Fum15
50 - - 90.0
271
48
3D
4umzB00 - 7.5
52
48 - - 75.1
53
47 - - 73.5
55
46 - - 93.4
54
46 - - 79.4
56
45 - - 77.2
58
44 - - 84.2
57
44 - - 76.8
59
44 - - 94.5
60
43 - - 85.1
61
42 - - 62.1
62
40 - - 79.5
63
39 - - 94.2
64
35 - - 90.6
65
34 - - 84.2
68
31 - - 91.7
67
31 - - 85.0
66
31 - - 74.0
69
Eurofung
30 - - 91.1
70
28 - - 90.6
71
28 - - 46.9
95
28
3D
3tikD00 - 27.7
72
27 - - 95.7
299
27
3D
5xxiA00 - 47.6
73
26 - - 69.1
75
24 - - 76.4
76
24 - - 92.3
120
24
3D
2w0bA00 - 4.6
74
24 - - 36.8
78
23 - - 94.3
77
23 - - 33.4
79
22 - - 73.5
103
22
3D
3iw2A00 - 27.1
81
22 - - 92.3
80
22 - - 62.9
83
21 - - 19.7
84
21 - - 76.8
82
21 - - 18.5
86
20 - - 77.4
85
20 - - 41.1
87
20 - - 22.0
88
19 - - 90.0
89
18 - - 43.6
91
17 - - 96.6
90
17 - - 82.0
93
16 - - 85.1
377
16
3D
4lhtB00 - 7.5
94
16 - - 96.0
92
16 - - 71.9
140
15
3D
5lieB00 - 0.3
98
15 - - 92.9
97
15 - - 94.9
99
14 - - 65.5
102
14 - - 85.7
100
14 - - 53.3
185
14
3D
2zqxC00 - 24.1
101
14 - - 90.3
104
14 - - 88.1
106
13 - - 74.0
107
13 - - 31.0
109
13 - - 15.1
108
13 - - 0.0
110
13 - - 80.2
105
13 - - 41.8
116
12 - - 10.6
112
12 - - 48.5
127
12
3D
2wm5A00 - 1.9
119
12 - - 72.9
117
12 - - 0.0
118
12 - - 15.5
115
12 - - 71.4
111
12 - - 62.3
113
12 - - 71.8
114
12 - - 76.7
121
11 - - 14.6
128
10 - - 0.0
129
10 - - 93.8
126
10 - - 93.6
122
10 - - 69.9
130
10 - - 91.6
124
10 - - 34.2
123
10 - - 64.2
125
10 - - 68.7
169
E
10
3D
3el3B00 - 11.7
134
9 - - 13.9
273
9
3D
2xfhA00 - 10.6
133
9 - - 0.0
131
9 - - 46.9
135
9 - - 47.3
132
9 - - 34.3
136
9 - - 89.9
145
8 - - 75.8
141
8 - - 7.7
143
8 - - 15.5
144
8 - - 13.3
138
8 - - 72.2
139
8 - - 71.6
137
8 - - 68.1
146
8 - - 87.6
159
7 - - 73.8
157
7 - - 65.6
158
Eurofung
7 - - 85.3
160
7 - - 74.6
152
7 - - 16.8
156
7 - - 6.5
151
7 - - 44.7
153
7 - - 10.0
154
7 - - 0.0
196
7
3D
5hdiB00 - 0.0
149
7 - - 54.0
147
S
7 - - 63.3
150
7 - - 78.7
148
7 - - 30.6
155
7 - - 19.3
165
6 - - 88.8
176
6 - - 67.3
172
6 - - 0.0
182
6 - - 80.5
164
6 - - 77.3
179
6 - - 66.7
177
6 - - 75.5
161
6 - - 75.3
178
6 - - 79.7
163
6 - - 76.0
170
6 - - 0.0
166
6 - - 12.9
162
6 - - 78.4
175
6 - - 68.5
181
6 - - 70.3
371
6
3D
2ve4B00 - 0.0
168
6 - - 7.8
173
6 - - 0.0
171
6 - - 0.0
174
6 - - 11.5
180
6 - - 42.2
167
6 - - 13.4
194
5 - - 8.3
203
5 - - 53.4
201
5 - - 17.2
188
Eurofung
5 - - 80.2
193
5 - - 6.6
204
5 - - 68.5
189
5 - - 46.7
187
5 - - 32.8
191
5 - - 16.2
186
Eurofung
5 - - 31.7
195
5 - - 0.0
200
5 - - 91.3
210
5 - - 74.4
205
5 - - 63.9
190
5 - - 26.9
184
5 - - 39.0
198
5 - - 9.9
207
5 - - 77.1
209
5 - - 76.7
183
5 - - 40.2
197
5 - - 7.7
208
5 - - 79.7
199
5 - - 13.9
192
5 - - 15.6
202
5 - - 56.7
206
5 - - 74.8
211
4 - - 35.6
225
4 - - 9.0
236
4 - - 79.0
232
4 - - 45.5
213
4 - - 54.4
220
4 - - 52.5
214
4 - - 21.6
224
4 - - 9.8
223
4 - - 10.8
215
4 - - 65.5
221
4 - - 75.0
239
4 - - 74.1
237
4 - - 32.5
242
4 - - 76.3
219
4 - - 51.7
217
4 - - 51.1
222
4 - - 82.4
241
4 - - 87.9
226
4 - - 10.5
235
4 - - 72.9
230
4 - - 5.9
218
4 - - 54.5
234
4 - - 60.2
375
4
3D
4dnjA00 - 0.0
240
4 - - 88.4
228
4 - - 0.3
233
4 - - 51.3
212
4 - - 17.9
227
4 - - 0.0
229
4 - - 5.5
216
4 - - 39.0
231
4 - - 9.1
292
3 - - 72.9
268
3 - - 7.1
296
3 - - 78.2
249
3 - - 9.2
285
3 - - 32.2
247
3 - - 12.2
250
3 - - 29.7
248
3 - - 29.3
280
3 - - 65.1
269
3 - - 0.3
267
3 - - 11.9
274
3 - - 1.6
255
3 - - 35.5
284
3 - - 51.9
270
3 - - 0.6
251
3 - - 11.2
262
3 - - 1.6
253
3 - - 21.7
266
3 - - 0.0
283
3 - - 37.8
275
3 - - 0.0
246
3 - - 23.0
254
3 - - 41.3
297
3 - - 41.4
281
3 - - 0.0
286
3 - - 55.2
295
3 - - 23.4
282
3 - - 0.0
243
3 - - 17.4
279
3 - - 1.8
277
3 - - 4.6
264
3 - - 4.2
261
3 - - 0.0
290
3 - - 63.3
256
3 - - 61.7
244
3 - - 11.6
278
3 - - 0.0
252
3 - - 24.8
263
3 - - 0.0
294
3 - - 65.6
259
3 - - 73.9
257
3 - - 56.7
288
3 - - 38.9
265
3 - - 0.0
258
3 - - 66.3
272
3 - - 0.0
276
3 - - 4.6
293
3 - - 40.9
291
3 - - 71.4
260
3 - - 13.8
289
3 - - 68.3
287
3 - - 60.2
245
3 - - 24.0
390
2 - - 0.0
469
2 - - 36.7
467
2 - - 41.2
318
2 - - 25.1
448
2 - - 32.6
361
2 - - 0.0
474
2 - - 43.0
330
2 - - 36.0
404
2 - - 1.5
420
2 - - 40.5
378
2 - - 7.8
363
2 - - 7.1
308
2 - - 31.3
352
2 - - 0.0
455
2 - - 37.5
356
2 - - 1.5
414
2 - - 36.8
344
2 - - 43.4
425
2 - - 48.4
436
2 - - 2.3
341
2 - - 34.3
335
2 - - 38.5
411
2 - - 6.7
326
2 - - 34.6
382
2 - - 0.0
317
2 - - 23.2
386
2 - - 5.2
473
2 - - 36.2
319
2 - - 27.0
449
2 - - 29.3
447
2 - - 26.2
322
2 - - 33.1
403
2 - - 0.0
432
2 - - 9.9
468
2 - - 42.3
395
2 - - 0.0
401
2 - - 0.2
471
2 - - 45.3
450
2 - - 32.3
364
2 - - 9.6
309
2 - - 30.4
307
2 - - 27.6
343
2 - - 36.6
413
2 - - 1.4
379
2 - - 10.6
475
2 - - 37.2
376
2 - - 2.1
306
2 - - 7.7
405
Eurofung
2 - - 0.0
393
2 - - 9.2
423
2 - - 41.4
333
2 - - 36.3
358
Eurofung
2 - - 0.0
302
2 - - 29.3
372
2 - - 1.8
454
2 - - 31.0
360
Eurofung
2 - - 0.0
345
2 - - 41.5
387
2 - - 1.0
316
2 - - 31.5
389
Eurofung
2 - - 3.0
421
2 - - 44.5
415
2 - - 39.0
446
2 - - 23.3
331
2 - - 39.1
442
2 - - 34.8
391
2 - - 3.8
298
2 - - 18.7
312
2 - - 30.2
439
2 - - 3.3
437
2 - - 3.0
329
2 - - 36.8
327
2 - - 32.7
394
2 - - 0.9
357
2 - - 7.5
359
2 - - 0.0
334
2 - - 34.9
400
2 - - 0.0
424
2 - - 39.3
451
2 - - 35.4
470
2 - - 39.7
462
2 - - 40.0
438
2 - - 10.1
453
2 - - 35.4
328
2 - - 35.8
388
2 - - 10.7
410
2 - - 5.0
340
2 - - 46.4
365
2 - - 10.2
466
2 - - 41.2
320
2 - - 30.1
304
2 - - 30.8
430
2 - - 36.0
374
2 - - 0.6
461
2 - - 37.2
348
2 - - 3.2
380
2 - - 0.0
418
2 - - 42.6
367
2 - - 4.0
369
2 - - 0.7
444
2 - - 13.3
314
2 - - 29.8
456
2 - - 32.4
355
2 - - 2.1
408
Eurofung
2 - - 0.0
452
2 - - 33.6
463
2 - - 36.3
368
2 - - 0.0
303
2 - - 31.1
332
2 - - 35.8
396
2 - - 2.2
422
2 - - 38.8
347
2 - - 7.4
385
2 - - 0.4
349
2 - - 2.3
419
2 - - 38.1
373
2 - - 0.0
417
2 - - 39.4
392
Eurofung
2 - - 0.0
426
2 - - 42.4
435
2 - - 0.0
311
2 - - 32.2
441
2 - - 11.6
336
2 - - 36.6
325
2 - - 28.4
313
2 - - 11.1
443
2 - - 43.6
407
2 - - 8.0
409
2 - - 4.5
464
2 - - 41.5
350
2 - - 0.0
301
2 - - 10.2
472
2 - - 37.4
458
2 - - 34.0
433
2 - - 3.1
402
2 - - 2.6
323
2 - - 32.1
305
2 - - 28.7
406
2 - - 5.7
383
2 - - 2.8
476
2 - - 43.1
427
2 - - 33.9
429
2 - - 35.0
381
2 - - 6.4
337
2 - - 38.7
339
2 - - 37.0
412
2 - - 0.0
342
2 - - 40.0
315
2 - - 18.2
431
2 - - 35.3
346
2 - - 16.0
321
2 - - 33.5
445
2 - - 22.4
416
2 - - 37.1
460
2 - - 36.9
354
2 - - 6.1
399
2 - - 0.0
397
2 - - 0.0
370
2 - - 1.6
351
2 - - 3.9
324
2 - - 21.4
300
2 - - 28.0
434
2 - - 0.0
459
2 - - 35.3
457
2 - - 35.3
384
2 - - 1.1
366
2 - - 0.0
465
2 - - 43.3
398
2 - - 0.0
440
2 - - 39.7
310
2 - - 10.7
428
2 - - 36.2
338
2 - - 44.4
353
2 - - 2.5
362
2 - - 1.4
741
1 - - 0.0
544
1 - - 0.0
726
1 - - 0.0
735
1 - - 0.0
801
1 - - 0.0
480
1 - - 0.0
556
1 - - 0.0
782
1 - - 0.0
664
1 - - 0.0
609
1 - - 0.0
719
1 - - 0.0
813
1 - - 0.0
717
1 - - 0.0
607
1 - - 0.0
786
1 - - 0.0
563
1 - - 0.0
552
1 - - 0.0
508
1 - - 0.0
578
1 - - 0.0
643
1 - - 0.0
722
1 - - 0.0
795
1 - - 0.0
677
1 - - 0.0
679
1 - - 0.0
641
1 - - 0.0
635
1 - - 0.0
530
1 - - 0.0
626
1 - - 0.0
811
1 - - 0.0
764
1 - - 0.0
836
1 - - 0.0
825
1 - - 0.0
561
1 - - 0.0
682
1 - - 0.0
617
1 - - 0.0
686
1 - - 0.0
707
1 - - 0.0
709
1 - - 0.0
619
1 - - 0.0
832
1 - - 0.0
803
1 - - 0.0
518
1 - - 0.0
622
1 - - 0.0
743
1 - - 0.0
590
1 - - 0.0
779
1 - - 0.0
777
1 - - 0.0
695
1 - - 0.0
577
1 - - 0.0
579
1 - - 0.0
790
1 - - 0.0
678
1 - - 0.0
543
1 - - 0.0
492
1 - - 0.0
663
1 - - 0.0
652
1 - - 0.0
718
1 - - 0.0
608
1 - - 0.0
509
1 - - 0.0
507
1 - - 0.0
761
1 - - 0.0
564
1 - - 0.0
656
1 - - 0.0
814
1 - - 0.0
485
1 - - 0.0
730
1 - - 0.0
496
1 - - 0.0
644
1 - - 0.0
690
1 - - 0.0
595
1 - - 0.0
522
1 - - 0.0
778
1 - - 0.0
752
1 - - 0.0
618
1 - - 0.0
708
1 - - 0.0
763
1 - - 0.0
586
1 - - 0.0
517
1 - - 0.0
519
1 - - 0.0
820
1 - - 0.0
661
1 - - 0.0
582
1 - - 0.0
804
1 - - 0.0
756
1 - - 0.0
535
1 - - 0.0
630
1 - - 0.0
526
1 - - 0.0
744
1 - - 0.0
541
1 - - 0.0
529
1 - - 0.0
527
1 - - 0.0
628
1 - - 0.0
483
1 - - 0.0
591
1 - - 0.0
512
1 - - 0.0
794
1 - - 0.0
759
1 - - 0.0
838
1 - - 0.0
757
phenobarbital-inducible
1 - - 0.0
734
1 - - 0.0
688
1 - - 0.0
531
1 - - 0.0
516
1 - - 0.0
587
1 - - 0.0
545
1 - - 0.0
640
1 - - 0.0
589
1 - - 0.0
665
1 - - 0.0
560
1 - - 0.0
810
1 - - 0.0
497
1 - - 0.0
499
1 - - 0.0
728
1 - - 0.0
572
1 - - 0.0
502
1 - - 0.0
558
1 - - 0.0
533
1 - - 0.0
694
1 - - 0.0
657
1 - - 0.0
659
1 - - 0.0
634
1 - - 0.0
788
1 - - 0.0
593
1 - - 0.0
740
1 - - 0.0
506
1 - - 0.0
576
1 - - 0.0
824
1 - - 0.0
765
1 - - 0.0
481
1 - - 0.0
800
1 - - 0.0
484
1 - - 0.0
846
1 - - 0.0
815
1 - - 0.0
821
1 - - 0.0
565
1 - - 0.0
660
1 - - 0.0
776
1 - - 0.0
706
1 - - 0.0
687
1 - - 0.0
616
1 - - 0.0
645
1 - - 0.0
540
1 - - 0.0
689
1 - - 0.0
793
1 - - 0.0
588
1 - - 0.0
631
1 - - 0.0
691
1 - - 0.0
837
1 - - 0.0
702
1 - - 0.0
839
1 - - 0.0
612
1 - - 0.0
758
1 - - 0.0
733
1 - - 0.0
772
1 - - 0.0
528
1 - - 0.0
629
1 - - 0.0
627
1 - - 0.0
842
1 - - 0.0
805
1 - - 0.0
760
1 - - 0.0
676
1 - - 0.0
789
1 - - 0.0
787
1 - - 0.0
606
1 - - 0.0
716
1 - - 0.0
745
1 - - 0.0
731
1 - - 0.0
693
1 - - 0.0
534
1 - - 0.0
557
1 - - 0.0
559
1 - - 0.0
602
1 - - 0.0
712
1 - - 0.0
594
1 - - 0.0
633
1 - - 0.0
658
1 - - 0.0
791
1 - - 0.0
498
1 - - 0.0
672
1 - - 0.0
727
1 - - 0.0
823
1 - - 0.0
729
1 - - 0.0
809
1 - - 0.0
732
1 - - 0.0
703
1 - - 0.0
613
1 - - 0.0
768
1 - - 0.0
807
1 - - 0.0
796
1 - - 0.0
749
1 - - 0.0
843
1 - - 0.0
785
1 - - 0.0
747
1 - - 0.0
773
1 - - 0.0
555
1 - - 0.0
650
1 - - 0.0
671
1 - - 0.0
601
1 - - 0.0
711
1 - - 0.0
514
1 - - 0.0
792
1 - - 0.0
725
1 - - 0.0
490
1 - - 0.0
736
1 - - 0.0
668
1 - - 0.0
817
1 - - 0.0
819
1 - - 0.0
632
1 - - 0.0
603
1 - - 0.0
713
1 - - 0.0
567
1 - - 0.0
569
1 - - 0.0
696
1 - - 0.0
685
1 - - 0.0
822
1 - - 0.0
647
1 - - 0.0
649
1 - - 0.0
580
1 - - 0.0
673
1 - - 0.0
548
1 - - 0.0
750
1 - - 0.0
841
1 - - 0.0
835
1 - - 0.0
771
1 - - 0.0
826
1 - - 0.0
574
1 - - 0.0
504
1 - - 0.0
692
1 - - 0.0
701
1 - - 0.0
611
1 - - 0.0
478
1 - - 0.0
636
1 - - 0.0
520
1 - - 0.0
625
1 - - 0.0
495
1 - - 0.0
720
1 - - 0.0
501
1 - - 0.0
614
1 - - 0.0
704
1 - - 0.0
774
1 - - 0.0
571
1 - - 0.0
655
1 - - 0.0
486
1 - - 0.0
550
1 - - 0.0
844
1 - - 0.0
482
1 - - 0.0
748
1 - - 0.0
780
1 - - 0.0
769
1 - - 0.0
767
1 - - 0.0
808
1 - - 0.0
513
1 - - 0.0
536
1 - - 0.0
479
1 - - 0.0
620
1 - - 0.0
525
1 - - 0.0
477
1 - - 0.0
714
1 - - 0.0
604
1 - - 0.0
592
1 - - 0.0
511
1 - - 0.0
830
1 - - 0.0
674
1 - - 0.0
755
1 - - 0.0
573
1 - - 0.0
648
1 - - 0.0
585
1 - - 0.0
547
1 - - 0.0
549
1 - - 0.0
680
1 - - 0.0
818
1 - - 0.0
667
1 - - 0.0
669
1 - - 0.0
596
1 - - 0.0
568
1 - - 0.0
532
1 - - 0.0
503
1 - - 0.0
666
1 - - 0.0
770
1 - - 0.0
599
1 - - 0.0
597
1 - - 0.0
751
1 - - 0.0
554
1 - - 0.0
840
1 - - 0.0
698
1 - - 0.0
521
1 - - 0.0
724
1 - - 0.0
546
1 - - 0.0
515
1 - - 0.0
610
1 - - 0.0
700
1 - - 0.0
493
S
1 - - 0.0
542
1 - - 0.0
828
1 - - 0.0
537
1 - - 0.0
539
1 - - 0.0
638
1 - - 0.0
653
1 - - 0.0
784
1 - - 0.0
662
1 - - 0.0
581
1 - - 0.0
575
1 - - 0.0
834
1 - - 0.0
766
1 - - 0.0
670
1 - - 0.0
583
1 - - 0.0
798
1 - - 0.0
651
1 - - 0.0
624
1 - - 0.0
491
1 - - 0.0
710
1 - - 0.0
600
1 - - 0.0
505
1 - - 0.0
523
1 - - 0.0
489
1 - - 0.0
487
1 - - 0.0
762
1 - - 0.0
753
1 - - 0.0
684
1 - - 0.0
738
1 - - 0.0
553
1 - - 0.0
538
1 - - 0.0
562
1 - - 0.0
681
1 - - 0.0
637
1 - - 0.0
639
1 - - 0.0
812
1 - - 0.0
723
1 - - 0.0
829
1 - - 0.0
642
1 - - 0.0
827
1 - - 0.0
646
1 - - 0.0
705
1 - - 0.0
615
1 - - 0.0
510
1 - - 0.0
621
1 - - 0.0
494
1 - - 0.0
816
1 - - 0.0
845
1 - - 0.0
598
1 - - 0.0
783
1 - - 0.0
654
1 - - 0.0
566
Cytochrome P450 family 71 subfamily A polypeptide 12
1 - - 0.0
699
1 - - 0.0
697
1 - - 0.0
831
1 - - 0.0
775
1 - - 0.0
781
1 - - 0.0
584
1 - - 0.0
802
1 - - 0.0
739
1 - - 0.0
833
1 - - 0.0
737
1 - - 0.0
742
1 - - 0.0
623
1 - - 0.0
488
1 - - 0.0
500
1 - - 0.0
746
1 - - 0.0
605
1 - - 0.0
715
1 - - 0.0
524
1 - - 0.0
721
1 - - 0.0
754
1 - - 0.0
683
1 - - 0.0
806
1 - - 0.0
551
1 - - 0.0
675
1 - - 0.0
797
1 - - 0.0
799
1 - - 0.0
570
1 - - 0.0
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