The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Alpha trans-inducing (Alpha-TIF)
".
FunFam 1: Tegument protein VP16
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | G8HBG2 (/IPI) G8HBG2 (/IPI) P06492 (/IPI) P06492 (/IPI) Q65819 (/IPI) Q65819 (/IPI) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
2 | P06492 (/IMP) P06492 (/IMP) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | P06492 (/IMP) P06492 (/IMP) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
|
2 | P06492 (/IPI) P06492 (/IPI) |
|
Structural constituent of virion GO:0039660
The action of a molecule that contributes to the structural integrity of a virion.
|
2 | P06492 (/IDA) P06492 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-templated viral transcription GO:0039695
A transcription process that uses a viral DNA as a template.
|
22 |
P04486 (/ISS)
P04486 (/ISS)
P04486 (/ISS)
P04486 (/ISS)
P28938 (/ISS)
P30020 (/ISS)
P68335 (/ISS)
P68335 (/ISS)
P68335 (/ISS)
P68335 (/ISS)
(12 more) |
|
DNA-templated viral transcription GO:0039695
A transcription process that uses a viral DNA as a template.
|
4 | P06492 (/IDA) P06492 (/IDA) P09265 (/IDA) P09265 (/IDA) |
|
Interaction with host via substance released outside of symbiont GO:0044046
An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P06492 (/IMP) P06492 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P06492 (/IGI) P06492 (/IGI) |
|
Regulation of viral transcription GO:0046782
Any process that modulates the frequency, rate or extent of the transcription of the viral genome.
|
2 | P06492 (/IMP) P06492 (/IMP) |
|
Interaction with host GO:0051701
An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
2 | P06492 (/IMP) P06492 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Viral tegument GO:0019033
A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Host cell cytoplasm GO:0030430
The cytoplasm of a host cell.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Host cell cytoplasm GO:0030430
The cytoplasm of a host cell.
|
2 | Q65819 (/IMP) Q65819 (/IMP) |
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
2 | Q65819 (/IMP) Q65819 (/IMP) |
|
Host cell cytoplasmic vesicle GO:0044161
A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Host cell perinuclear region of cytoplasm GO:0044220
The host cell cytoplasm situated near, or occurring around, the host nucleus.
|
2 | P06492 (/IDA) P06492 (/IDA) |
|
Replication compartment GO:0046809
Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.
|
2 | P06492 (/IDA) P06492 (/IDA) |
