CATH Superfamily 1.10.1070.11

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit	550	3D	5dxuA05	-	94.2
2	Phosphatidylinositol 3-kinase catalytic subunit type 3	509		-	-	88.0
3	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	491		-	-	78.4
4	Phosphatidylinositol 4-kinase, catalytic, beta	402		-	-	73.0
5	Phosphatidylinositol 4-kinase, catalytic, alpha	302		-	-	79.7
6	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit	274	3D	4yknA08	-	70.4
10	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	273	3D	6c1sA05	-	68.6
7	Serine/threonine-protein kinase TOR	229		-	-	66.5
8	serine/threonine-protein kinase SMG1 isoform X2	213		-	-	67.9
9	Putative serine/threonine-protein kinase ATR	193		-	-	73.6
11	Serine-protein kinase ATM	172		-	-	71.6
12	Phosphatidylinositol 4-kinase alpha 1	158		-	-	92.6
13	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	142		-	-	68.2
14	Phosphatidylinositol 3-kinase, root isoform	141		-	-	74.9
15	Serine/threonine-protein kinase ATM	130		-	-	67.0
16	PIK1p Phosphatidylinositol 4-kinase	119		-	-	89.9
17	Serine/threonine-protein kinase TOR	116		-	-	43.0
18	DNA-dependent protein kinase catalytic subunit	115		-	-	82.8
19	Phosphatidylinositol 4-kinase beta 1	108		-	-	41.9
20	Serine/threonine-protein kinase TOR	104		-	-	68.5
21	Serine/threonine-protein kinase ATR, putative	74		-	-	75.4
22	Phosphatidylinositol 4-kinase stt4	73		-	-	70.6
23	serine/threonine-protein kinase SMG1 isoform X1	63		-	-	76.7
24	Serine/threonine-protein kinase ATR	61		-	-	55.5
25	Serine/threonine-protein kinase Tel1	56		-	-	43.9
26	Phosphotransferases/inositol or phosphatidylinositol kinase	41		-	-	86.6
27	Putative Phosphatidylinositol 4-kinase	36		-	-	28.8
28	Serine/threonine-protein kinase TOR	35		-	-	60.9
29	Serine/threonine-protein kinase TOR	30		-	-	90.3
30	Histone acetylase complex subunit Paf400	29		-	-	75.8
31	Phosphatidyl inositol 3-kinase	27		-	-	73.6
32	Protein kinase rad3	24		-	-	78.6
33	Serine/threonine-protein kinase MEC1	19		-	-	78.0
35	Phosphatidylinositol kinase PIK-D	18		-	-	17.3
34	Serine/threonine-protein kinase Tel1	18		-	-	20.9
36	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, putative	16		-	-	38.9
37	Phosphatidylinositol kinase PIK-L3	15		-	-	21.6
38	Serine/threonine-protein kinase Tel1	14		-	-	58.5
39	Serine/threonine-protein kinase TOR	14		-	-	89.2
41	DNA-dependent protein kinase catalytic subunit	13		-	-	88.4
40	Serine/threonine-protein kinase TOR	13		-	-	59.5
42	Phosphatidylinositol 3-kinase VPS34	13		-	-	73.1
43	Serine/threonine-protein kinase Tel1	12		-	-	5.9
44	NuA4 histone acetyltransferase subunit	12		-	-	80.6
46	Phosphatidylinositol 3-kinase, putative	10		-	-	26.8
45	Serine/threonine-protein kinase smg-1	10		-	-	73.7
47	Serine/threonine-protein kinase ATR	9		-	-	17.8
48	Phosphatidylinositol 3-kinase, putative	9		-	-	43.9
50	Phosphatidylinositol 3-kinase age-1	8		-	-	54.7
51	Phosphatidylinositol 3-and 4-kinase family protein	8		-	-	6.4
49	Ataxia telangiectasia mutated, putative	8		-	-	6.2
56	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit	7		-	-	32.6
52	Serine/threonine-protein kinase Tel1	7		-	-	27.8
53	Serine/threonine-protein kinase ATM	7		-	-	46.0
54	serine/threonine-protein kinase ATM	7		-	-	16.8
55	PIKK family atypical protein kinase	7		-	-	93.6
59	Phosphatidylinositol 3-and 4-kinase family protein	6		-	-	72.3
57	PIKK family atypical protein kinase	6		-	-	78.5
58	MTOR isoform 6	6		-	-	40.1
63	GTOR	5		-	-	3.4
62	Phosphatidylinositol 3-and 4-kinase, putative	5		-	-	0.0
60	Predicted protein	5		-	-	64.6
70	Phosphatidylinositol 3-kinase catalytic subunit type 3	5	3D	5ennA03	-	20.1
61	Serine/threonine-protein kinase ATR	5		-	-	22.8
65	PIKK family atypical protein kinase	4		-	-	66.8
74	DJ576K7.1 FK506 binding protein 12-rapamycin associated protein 1	4		-	-	46.6
64	PIKK family atypical protein kinase	4		-	-	70.5
68	Phosphatidylinositol 3-and 4-kinase family protein	4		-	-	24.9
73	Dual specificity protein phosphatase PHS1	4		-	-	9.2
69	Phosphoinositide-3-kinase, class 3	4		-	-	9.2
72	Phosphatidylinositol kinase, putative	4		-	-	3.7
67	AGAP003967-PA	4		-	-	13.3
66	NUC194_domain/Phosphatidylinositol_3-_and_4 -kinase_-_putative	4		-	-	17.7
71	PIKK family atypical protein kinase	4		-	-	64.2
75	Non-specific serine/threonine protein kinase	3		-	-	32.8
78	Phosphatidylinositol 3-kinase catalytic subunit, putative	3		-	-	53.9
80	Acyl carrier protein	3		-	-	64.3
77	Uncharacterized protein	3		-	-	9.2
79	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit	3		-	-	7.9
76	Phosphatidylinositol 4-kinase	3		-	-	5.6
82	Non-specific serine/threonine protein kinase	2		-	-	0.6
89	Uncharacterized protein	2		-	-	3.2
95	Phosphatidylinositol 3-kinase piki-1	2		-	-	15.6
87	Uncharacterized protein	2		-	-	3.4
94	Phosphatidylinositol 3-and 4-kinase family protein	2		-	-	41.6
86	Smilar to phosphatidylinositol 3-or 4-kinase	2		-	-	0.0
93	Serine/threonine-protein kinase TOR	2		-	-	32.6
81	Phosphatidylinositol kinase domain protein, putative	2		-	-	31.9
85	Chromosome 12, whole genome shotgun sequence	2		-	-	12.6
92	Predicted protein	2		-	-	0.0
96	Phosphatidylinositol 3-kinase-related protein kinase	2		-	-	38.2
84	Phosphatidylinositol 3-kinase, putative	2		-	-	0.0
88	DNA-dependent protein kinase catalytic subunit	2		-	-	3.5
83	Serine/threonine-protein kinase TEL1	2		-	-	0.0
91	Uncharacterized protein	2		-	-	40.6
90	Uncharacterized protein	2		-	-	33.0
140	Uncharacterized protein	1		-	-	0.0
112	PIKK family atypical protein kinase	1		-	-	0.0
102	Predicted protein	1		-	-	0.0
121	Uncharacterized PI3/PI4-kinase family protein C1F5.11c	1		-	-	0.0
133	Serine/threonine-protein kinase TOR	1		-	-	0.0
134	Uncharacterized protein	1		-	-	0.0
98	PIKK family atypical protein kinase	1		-	-	0.0
119	Uncharacterized protein	1		-	-	0.0
105	Protein kinase, DNA-activated, catalytic subunit	1		-	-	0.0
107	Uncharacterized protein	1		-	-	0.0
109	Predicted protein	1		-	-	0.0
146	Serine/threonine-protein kinase TOR	1		-	-	0.0
117	Phosphatidylinositol 3-kinase catalytic subunit type 3	1		-	-	0.0
115	Uncharacterized protein	1		-	-	0.0
144	Uncharacterized protein	1		-	-	0.0
125	Uncharacterized protein	1		-	-	0.0
127	Uncharacterized protein	1		-	-	0.0
136	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit	1		-	-	0.0
129	Uncharacterized protein	1		-	-	0.0
138	Uncharacterized protein	1		-	-	0.0
130	Uncharacterized protein	1		-	-	0.0
111	Uncharacterized protein	1		-	-	0.0
101	Uncharacterized protein	1		-	-	0.0
122	mDNApk3', putative	1		-	-	0.0
143	Uncharacterized protein	1		-	-	0.0
114	Uncharacterized protein	1		-	-	0.0
139	Uncharacterized protein	1		-	-	0.0
97	Ataxia telangiectasia mutated, putative	1		-	-	0.0
128	Uncharacterized protein	1		-	-	0.0
126	Uncharacterized protein	1		-	-	0.0
99	Uncharacterized protein	1		-	-	0.0
104	Serine/threonine-protein kinase tel1	1		-	-	0.0
137	Uncharacterized protein	1		-	-	0.0
135	Uncharacterized protein	1		-	-	0.0
141	Uncharacterized protein	1		-	-	0.0
132	Predicted protein	1		-	-	0.0
103	Putative phosphatidylinositol kinase	1		-	-	0.0
113	Serine/threonine-protein kinase Tel1	1		-	-	0.0
120	Uncharacterized protein	1		-	-	0.0
123	Uncharacterized protein	1		-	-	0.0
110	Non-specific serine/threonine protein kinase	1		-	-	0.0
142	Uncharacterized protein	1		-	-	0.0
131	Uncharacterized protein	1		-	-	0.0
100	Putative actin-fragmin kinase DDB_G0279609	1		-	-	0.0
106	Uncharacterized protein	1		-	-	0.0
108	Uncharacterized protein	1		-	-	0.0
116	Phosphatidylinositol 3-and 4-kinase family protein	1		-	-	0.0
118	Uncharacterized protein	1		-	-	0.0
145	Phosphatidylinositol 3-kinase catalytic subunit, putative	1		-	-	0.0
124	Uncharacterized protein	1		-	-	0.0

Network disruptions

CATH Superfamily 1.10.1070.11

Phosphatidylinositol 3-/4-kinase, catalytic domain

Functional Families

Browse Functional Families