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1 keywords

CATH Domain 6r9qA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.70 Cathepsin B; Chain A
Homologous Superfamily 3.90.70.10 Cysteine proteinases

Domain Context

CATH Clusters

Superfamily Cysteine proteinases
Functional Family PAN2-PAN3 deadenylation complex catalytic subunit PAN2

Enzyme Information

3.1.13.4
Poly(A)-specific ribonuclease.
based on mapping to UniProt P53010
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.

UniProtKB Entries (1)

P53010
PAN2_YEAST
Saccharomyces cerevisiae S288C
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

PDB Structure

PDB 6R9Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Tang, T.T.L., Stowell, J.A.W., Hill, C.H., Passmore, L.A.
Nat.Struct.Mol.Biol.
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