CATH Domain 6i1dA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Cleavage and polyadenylation specificity factor

Enzyme Information

3.1.27.-

Endoribonucleases producing other than 5'-phosphomonoesters.

based on mapping to UniProt Q06224

UniProtKB Entries (1)

MPE1_YEAST

Saccharomyces cerevisiae S288C

Protein MPE1

PDB Structure

PDB	6I1D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex. Hill, C.H., Boreikaite, V., Kumar, A., Casanal, A., Kubik, P., Degliesposti, G., Maslen, S., Mariani, A., von Loeffelholz, O., Girbig, M., Skehel, M., Passmore, L.A. Mol.Cell