×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily von Hippel-Lindau disease tumour suppressor, beta domain
Functional Family von Hippel-Lindau disease tumor suppressor

Enzyme Information

UniProtKB Entries (1)

Q16665
HIF1A_HUMAN
Homo sapiens
Hypoxia-inducible factor 1-alpha

PDB Structure

PDB 6GMR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
Lucas, X., Van Molle, I., Ciulli, A.
J. Med. Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...