CATH Domain 6g1lA00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.280	MYOD Basic-Helix-Loop-Helix Domain, subunit B
	4.10.280.10	Helix-loop-helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Helix-loop-helix DNA-binding domain
Functional Family	microphthalmia-associated transcription factor isoform X1

Enzyme Information

UniProtKB Entries (1)

MITF_MOUSE

Mus musculus

Microphthalmia-associated transcription factor

PDB Structure

PDB	6G1L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	MITF has a central role in regulating starvation-induced autophagy in melanoma. Moller, K., Sigurbjornsdottir, S., Arnthorsson, A.O., Pogenberg, V., Dilshat, R., Fock, V., Brynjolfsdottir, S.H., Bindesboll, C., Bessadottir, M., Ogmundsdottir, H.M., Simonsen, A., Larue, L., Wilmanns, M., Thorsson, V., Steingrimsson, E., Ogmundsdottir, M.H. Sci Rep