CATH Domain 6ew3B00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Class B metallo-beta-lactamase

Enzyme Information

UniProtKB Entries (1)

D1MEN9_PSEAI

Pseudomonas aeruginosa

Metallo-beta-lactamase VIM-2

PDB Structure

PDB	6EW3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases. Zhang, D., Markoulides, M.S., Stepanovs, D., Rydzik, A.M., El-Hussein, A., Bon, C., Kamps, J.J.A.G., Umland, K.D., Collins, P.M., Cahill, S.T., Wang, D.Y., von Delft, F., Brem, J., McDonough, M.A., Schofield, C.J. Bioorg. Med. Chem.