CATH Domain 6cvyA02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

A0A0B4WYC6_9HEPC

Hepacivirus C

NS3 protease

PDB Structure

PDB	6CVY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants. Rusere, L.N., Matthew, A.N., Lockbaum, G.J., Jahangir, M., Newton, A., Petropoulos, C.J., Huang, W., Kurt Yilmaz, N., Schiffer, C.A., Ali, A. ACS Med Chem Lett