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1 keywords

CATH Domain 6co3L01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

P05067
A4_HUMAN
Homo sapiens
Amyloid-beta precursor protein

PDB Structure

PDB 6CO3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta.
Arndt, J.W., Qian, F., Smith, B.A., Quan, C., Kilambi, K.P., Bush, M.W., Walz, T., Pepinsky, R.B., Bussiere, T., Hamann, S., Cameron, T.O., Weinreb, P.H.
Sci Rep
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